天然产物研究与开发 ›› 2018, Vol. 30 ›› Issue (增刊1): 137-140.doi: 10.16333/j.1001-6880.2018.S.025

• 研究简报 • 上一篇    下一篇

一种新的连翘中连翘苷的HPLC含量测定方法

李刚1  , 魏庆红1*  , 段伟伟1   

  1. 亳州市中药材进出口检测中心,亳州 236800
  • 出版日期:2018-07-31 发布日期:2018-07-31
  • 基金资助:

    物联网技术与中药材智能化生产的研究与示范

A New Method for the Content Determination of Forsythin in Forsythia suspensa

LI Gang1, WEI Qing-hong1*, DUAN Wei-wei1   

  1. Import and Export of Chinese medicinal materials testing center of Bozhou,Bozhou 236800,China
  • Online:2018-07-31 Published:2018-07-31

摘要: 本研究为验证一种简便高效的连翘样品中连翘苷含量测定方法,以便更简洁的控制连翘药材的质量。实验过程中采用高效液相色谱法测定超声法所制得连翘样品中连翘苷的含量,并采用SPSS16.0统计软件对制得样品中连翘苷含量与中国药典法所得结果做统计学分析。 超声法所制得连翘样品中连翘苷含量均符合《中国药典》所规定的药品质量标准分析方法验证指导原则,且与中国药典法所得结果无显著性差异。 超声法简化了样品前处理过程,所测结果准确高效,具有较大的推广价值。

关键词: 连翘, 高效液相色谱法, 连翘苷, 超声法

Abstract: In order to control the quality of Forsythia suspensa,a simple and effective method for determining the content of Forsythia suspensa was studied.The content of forsythrin in the samples of Forsythia suspensa was determined by high performance liquid chromatography (HPLC).The content of Forsythia suspensa in the samples was analyzed by SPSS 16.0 software and the results obtained by Chinese pharmacopoeia method were analyzed statistically.The contents of Forsythia suspensa in the samples prepared by ultrasonic method were in accordance with the guidelines for the analysis of drug quality standards stipulated in the Chinese Pharmacopoeia,and there was no significant difference between the results obtained by the Chinese Pharmacopoeia method and the results obtained by the Chinese Pharmacopoeia method.Ultrasonic method simplifies sample pretreatment processThe measured results are accurate and efficient,and have great value of popularization.

Key words: Forsythia suspensa, HPLC, forsythin, ultrasonic method

中图分类号: 

R284.2