天然产物研究与开发 ›› 2018, Vol. 30 ›› Issue (增刊1): 153-156.doi: 10.16333/j.1001-6880.2018.S.028

• 研究简报 • 上一篇    下一篇

汉麻叶中大麻二酚提取工艺研究

高宝昌*,孙宇峰,张旭,田媛,石雨,崔宝玉   

  1. 黑龙江省科学院大庆分院,大庆 163316
  • 出版日期:2018-07-31 发布日期:2018-07-31

The Extraction Technology of Cannabidiol in Hemp Leaves

GAO Bao-chang*, SUN Yu-feng, ZHANG Xu, TIAN Yuan, SHI Yu, CUI Bao-yu   

  1. Daqing Branch of Heilongjiang Academy of Sciences,Daqing 163319,China
  • Online:2018-07-31 Published:2018-07-31

摘要: 通过对汉麻叶中大麻二酚提取方式的选择与筛选,考察了实验因素对提取效率的影响,确定最佳提取工艺为无水乙醇作为提取试剂、超声震荡15 min、料液比为1∶20、提取次数3次的实验方法。同时对大麻二酚的纯化工艺进行了研究,考察了大孔吸附树脂对大麻二酚的吸附和洗脱能力,确定DM130大孔吸附树脂对大麻二酚的纯化能力较强。利用液相色谱、质谱、核磁等仪器对产品进行表征,实现大麻二酚简单、高效的提取纯化。

关键词: 汉麻, 大麻二酚, 提取, 纯化

Abstract: leaves.The optimized conditions were extract with ethyl alcohol,ultrasound-assisted oscillate for 15 minutes,ratio of sample to solvent 1∶20,extraction 3 times.Meanwhile,the purification process of cannabidiol was also studied.The adsorption and elution capacity of cannabidiol by macroporous adsorption resin were investigated.The optimized macroporous adsorption resin is DM130.The product was characterized by HPLC,LCMS and HNMR.Finally,the cannabidiol of extracting and purification was established.

Key words: hemp, cannabidiol, extraction, purification

中图分类号: 

O629.9 R284.2