天然产物研究与开发 ›› 2019, Vol. 31 ›› Issue (2): 363-371.doi: 10.16333/j.1001-6880.2019.2.028

• 综述 • 上一篇    

2011~2017年新农药活性成分及天然产物药效团衍生法在农药分子设计中的应用

刘伟杰,李庆山,徐凤波*   

  1. 南开大学化学学院 元素有机化学国家重点实验室,天津 300071;
  • 出版日期:2019-03-07 发布日期:2019-03-07

New active ingredients of pesticides from 2011 to 2017 and application of natural products derivatization method in agrochemical molecular design

LIU Wei-jie,LI Qing-shan,XU Feng-bo*   

  1. State Key Laboratory of Elemento-Organic Chemistry,College of Chemistry,NanKai University,TianJin 300071,China
  • Online:2019-03-07 Published:2019-03-07

摘要: 统计了全球范围内首次登记日期位于2011~2017年的102种(不包含生物农药)农药活性成分,并以此为研究对象综述分析了SND(Synthetic natural derived)和NP(Natural product)类农药分子的天然产物来源、作用机制及在农药活性分子中的占比等,综合评估天然产物药效团衍生法在农药分子开发设计中的重要性,并在此基础上提供对未来发展方向。

关键词: 新农药活性成分, 天然产物药效团衍生法, 农药分子设计, 作用机制

Abstract: Based on the analysis of 102 new active ingredients registered for pesticides worldwide from 2011 to 2017,the natural product source,action mode and the share in new active ingredients studied of “SND(Synthetic Natural Derived)” categories and “NP (Natural Product)” categories were reviewed.Furthermore,the significance of natural products derivatization method in the design and developement of pesticides molecular was comprehensively estimated,and the prospects of this method were also put forward.

Key words: new active ingredients, natural products derivatization method, pesticides molecular design, action mode

中图分类号: 

R9142 O629.9