NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2015, Vol. 27 ›› Issue (4): 559-561.doi: 10.16333/j.1001-6880.2015.04.001

• Article •     Next Articles

A New Lactone Aldehyde Compound Isolated from Secondary Metabolites of Marine Fungus Penicillium griseofulvum

XU Yan,TIAN Sha-sha,ZHU Hua-jie*   

  1. Chinese Center for Chirality,the Key laboratory of Medicinal Chemistry and Molecular Diagnostics,Hebei University,071002,Baoding,Hebei Provence of China
  • Online:2015-04-28 Published:2015-05-08

Abstract: Three chemical constituents were separated and purified from marine-derived fungus Penicillium griseofulvum by silica gel column chromatography,semipreparative HPLC,ODS column chromatography and Sephadex LH-20 column chromatography.On the basis of spectral data (1D NMR,2D NMR and high resolution MS),their structures were elucidated as 2-(6-hydroxy-5,7-dimethylbenzofuranone-4-yl)acetaldehyde (1),terephthalic acid bis(2-ethyl-hexyl) ester (2) and bis(2ethylhexyl) adipate (3).Compound 1 was a new compound.

Key words: marine fungus, Penicillium griseofulvum, secondary metabolites, NMR

CLC Number: