Research progress on chemical constituents,pharmacological activities and clinical application of Euphorbia kansui

doi:10.16333/j.1001-6880.2022.4.018

Abstract

Abstract:

The dry root tuber of Euphorbia kansui T.N.Liou ex T.P.Wang(Euphorbia genus in Euphorbiaceae) is a unique Chinese herbal medicine in China.The main chemical constituents and active components of E. kansui are jatrophane diterpenes,ingenane diterpenes,euphane triterpenes and tirucallane triterpenes,which have many pharmacological activities such as anti-tumor,anti-virus,anti-inflammatory,insecticidal,antioxidant and immune system inhibition.This review comprehensively summarized 102 terpenes and 14 steroids and their structural characteristics,and systematically summarized the pharmacological activity,processing and clinical application of E. kansui,in order to provide reference for clinical rational drug use,quality control,resource comprehensive utilization and development of E. kansui.

Key words: Euphorbia kansui, diterpenes, triterpenes, pharmacological activity, clinical application

CLC Number:

R932

MA Li, MENG Xian-hua, YANG Jun-li. Research progress on chemical constituents,pharmacological activities and clinical application of Euphorbia kansui[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2022, 34(4): 699-712.

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Research progress on chemical constituents,pharmacological activities and clinical application of Euphorbia kansui

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