天然产物研究与开发 ›› 2017, Vol. 29 ›› Issue (8): 1439-1448.doi: A10.16333/j.1001-6880.2017.8.028

• 综述 • 上一篇    下一篇

桂花非挥发性成分及药理活性研究进展

吴超然1,房仙颖1*,萧伟2*   

  1. 1南京林业大学,南京 210037;2江苏康缘药业股份有限公司,连云港 222001
  • 出版日期:2017-08-28 发布日期:2017-08-28
  • 基金资助:

    国家林业局林业公益性行业科研基金(201404601);江苏省高校自然科学研究 面上项目(16KJB220002);江苏高校品牌专业建设工程(PPZY2015C221);南京林业大学大学生创新训练计划(2015sjcx041)

Review on Non-volatile Components and Pharmacological Activity of  Osmanthus fragrans

WU Chao-ran1, FANG Xian-ying1*, XIAO Wei2*   

  1. 1Nanjing Forestry University, Nanjing 210037, China; 2Jiangsu Kanion Pharmaceutical Co.,Ltd., Lianyungang 222001, China
  • Online:2017-08-28 Published:2017-08-28

摘要: 桂花在我国具有悠久的栽培与研究历史,目前的研究多集中于食用、精油和浸膏等方面。为了阐明桂花的综合利用价值,本文对桂花中的非挥发性成分的提取、分离、鉴定及其药学活性研究进行了综述。桂花的非挥发性成分包括黄酮类、萜类、木脂素类和苯丙素类等。桂花提取物具有抗炎、抗菌、抗氧化、抑制黑色素合成、细胞毒、抗衰老等药理学活性。通过对桂花提取方法和活性成分的研究,为其深度开发和高效综合利用提供参考。

关键词: 桂花, 非挥发性成分, 提取, 药理作用

Abstract: Osmanthus fragrans has a long history of cultivation and research in China. The present studies about  O.fragrans  mainly focus on food processing,essential oil and concrete. In order to clarify the comprehensive utilization value of  O.fragrans, the extraction,isolation,identification and pharmacological activities of the non-volatile components of  O.fragrans  were summarized in this review. The non-volatile components in O.fragrans  include flavonoids, terpenes, lignans and phenylethanoids, etc Osmanthus extracts showed anti-inflammation, anti-bacteria,antioxidation, melanin synthesis-inhibition, cytotoxicity, anti-aging and other pharmacological activities.The study on the extraction methods and the active components can provide reference for the further development and utilization of  O.fragrans.

Key words: Osmanthus fragrans, non-volatile constituents0, extraction, pharmacological activity

中图分类号: 

R284