无梗五加根中苯丙素类化合物的研究

doi:A

天然产物研究与开发 ›› 2012, Vol. 23 ›› Issue (4): 469-472.doi: A

无梗五加根中苯丙素类化合物的研究

于凯，宋洋，路阳，熊志立，李发美^*

沈阳药科大学药学院，沈阳 110016

出版日期:2012-04-26 发布日期:2012-05-16

Phenylpropanoids from Roots of Acanthopanax sessiliflorus (Rupr. et Maxim.) Seem.

YU Kai, SONG Yang, LU Yang, XIONG Zhi-li, LI Fa-mei^*

School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China

Online:2012-04-26 Published:2012-05-16
Supported by:
This work was supported by the Education Department of Liaoning Province 2009 Key laboratory of colleges and universities plan scientific research projects (No. 2009S101).

摘要/Abstract

摘要： 从无梗五加（Acanthopanax sessiliflorus ( Rupr. et Maxim. ) Seem.）根70%乙醇提取物的乙酸乙酯层中提取分离得到8个苯丙素类化合物。经理化和波谱分析鉴定为(+)-表芝麻脂素(1)、(–)-芝麻脂素(2)、赛菊芋黄素(3)、洒维宁(4)、咖啡酸甲酯(5)、对羟基桂皮酸(6)、(–)-丁香脂素(7)、(+)-松脂素(8)。化合物8是首次从五加科植物中分离得到，化合物1和5是首次从五加属植物中分离得到, 化合物3、6和7是首次从该植物中分离得到。

关键词: 无梗五加根, 苯丙素类化合物, (+)-表芝麻脂素, 咖啡酸甲酯, (+)-松脂素

Abstract: Eight phenylpropanoids were isolated from the ethyl acetate fraction of the 70% ethanol extract of the roots of Acanthopanax sessiliflorus (Rupr. et Maxim.) Seem.. Their structures were elucidated by physicochemical properties and spectroscopic analysis as (+)-episesamin (1), (–)-sesamin (2), helioxanthin (3), savinin (4), caffeic acid methyl ester (5), p-hydroxycinnamic acid (6), (–)-syringaresinol (7), and (+)-medioresinol (8). Compound 8 was isolated from Araliaceae for the first time, compounds 1 and 5 were obtained from Acanthopanax genus for the first time, and compounds 3, 6, and 7 were isolated from this plant for the first time.

Key words: Acanthopanax sessiliflorus (Rupr. et Maxim.) Seem., phenylpropanoids, (+)-episesamin, caffeic acid methyl ester, (+)-medioresinol

中图分类号:

R284.1 Q946. 91

于凯，宋洋，路阳，熊志立，李发美. 无梗五加根中苯丙素类化合物的研究[J]. 天然产物研究与开发, 2012, 23(4): 469-472.

YU Kai, SONG Yang, LU Yang, XIONG Zhi-li, LI Fa-mei. Phenylpropanoids from Roots of Acanthopanax sessiliflorus (Rupr. et Maxim.) Seem.[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2012, 23(4): 469-472.

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无梗五加根中苯丙素类化合物的研究

Phenylpropanoids from Roots of Acanthopanax sessiliflorus (Rupr. et Maxim.) Seem.

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