沙棘黄酮提取进展

doi:A

摘要/Abstract

摘要： 沙棘黄酮是食药两用植物沙棘主要的保健与药用成分，具有重要的生理活性，能够清除体内的自由基，具体防治心血管疾病和抗衰老的作用。本文概述了国内外对沙棘资源的开发利用研究状况，综述了沙棘黄酮类化合物提取方法的最新研究进展，为充分利用沙棘资源和开发沙棘黄酮提供科学研究基础。

关键词: 沙棘, 黄酮类化合物, 提取

Abstract: Seabuckthorn flavonoids are a major healthcare and pharmaceutical ingredients of seabuckthorn. They have important physiological activities that can remove free radicals, treat cardiovascular disease, and be anti-aging. To provide scientific basis for utilizing of sea-buckthorn resources and exploration of seabuckthorn flavonoids, an overview of sea buckthorn flavonoids extraction of the latest research advances was completed in this paper.

Key words: seabuckthorn, ketone category compound, extraction

中图分类号:

Q946.91 R284.2

彭游，汤明，胡小铭，邓泽元. 沙棘黄酮提取进展[J]. 天然产物研究与开发, 2012, 23(4): 562-567.

PENG You, Tang Ming, HU Xiao-ming, DENG Ze-yuan. Advances in Extraction of Flavonoids in Seabuckthorn[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2012, 23(4): 562-567.

参考文献

1 Zhun WJ(朱万靖),Li PD(倪培德),Jiang ZW(江志炜).Research on optimum extraction process of sea hippohae flavonoids.Chin Oil Fat(中国油脂),2000,25 (5):35-37.
2 Hollman PCH,Hertog MGL,Katan MB.Analysis and health effects of flavonoids.Food Chem,1996,57 (1):43- 46.
3 Rosch D,Krumbein A,Mugge C,et al.Structural investigations of flavonol glycosides from sea buckthorn (Hippophae rhamnoides) pomace by NMR spectroscopy and HPLC-ES/MS(n).J Agric Food Chem,2004,52: 4039-4046.
4 Zhan P(章平),Sun B(孙斌),Yang HJ(杨煌建),et al.Study of flavonoids from seed residues of Hippophae rhamnoides L. on apoptosis of human mammary carcinoma Bcap-37 cells.J Eastchina Nor Univ,Nat Sci(华东师范大学学报,自科版),2004,4,91-96.
5 Vinatoru M.An overview of the ultrasonically assisted extraction of bioactive principles from herbs. Ultrason Sonochem,2001,8:303- 313.
6 Tian CJ,Nan P,Chen JK,et a1.Volatile composition of Chinese Hippophae rhamnoides and its chemotaxonomicimplications．Biochem Sys Ecol,2004,32:431-441.
7 Yue ME,Jiang TF,Shi YP.Fast determination of flavonoids in Hippophae rhamnoides and its medicinal preparation by capillary zone electrophoresis using dimethyl-13-eyclodextrin as modifier.Talanta,2004,(62): 695-699.
8 Liu XJ(刘锡建),Wang YH(王艳辉),Ma RY(马润宇).Study on extracting and refining total flavones from marc of sea buckthorn.Food Sci(食品科学),2004,25(6):138-141.
9 Liu XJ(刘锡建),Wang YH(王艳辉),Ma RY(马润宇).Refinement of total flavonoids of Hippophae with macroporous adsorption resins.Chin Oil Fat(中国油脂),2004,29 (5):37-39.
10 Xi YN(忻耀年).Flavonoids preparation techniques and processes. Seabuckthorn(沙棘),2002,15 (1):15-19.
11 ZhaoYQ(赵玉琪),Yin LJ(殷丽君).Extraction of flavonoids from Hippophae rhamnoides L. leaves and their antioxidant activity.Sci Tech Food Ind(食品工业科技),2006,(4):70-75.
12 RuanDL(阮栋梁),Wang H(王晖),Li H(李和).Isolation and identification of flavonoids in seabuckthorn leaves. Seabuckthorn(沙棘),2002,15(4):32-34.
13 Liu Y(刘莹).Research of extraction of ketone category compound from sallowthorn. Chem Biol Engin (化学与生物工程),2005,22(7):50-51.
14 Wang SY(王尚义),ZhangYX(郑玉霞),Liu SP(刘声普).The extraction technical studies of total flavanones in the sea-buckthorn leaf by water.Seabuckthorn(沙棘),2001,14(2):27-29.
15 Wang ZY(王振宇),Xia XH(夏祥慧),Li HJ(李宏菊).Optimization of extraction process of total flavonoids form big-fruited sea-buckthorn by response surface method.J Northeast Forest Univ(东北林业大学学报), 2009,37(6):30-32.　
16 Wang SL(王树林).Study on the extraction technology of flavonoids from leaves of Hippophe rhamnoides Linn.Food Res Dev(食品研究与开发),2008,29(8):110-113.
17 Zhen J(郑京).Extraction and determination of the total flavonoids in Hippopae.Jiangsu Chem Ind(江苏化工), 2008,36(1),36-38.
18 Yu BX(袁本香),Zhang DH(张东河).The extraction process of total flavonoids in seabuckthorn fruit.Sci Tech Assoc Forum(科协论坛),2007,9:52-53.
19 Zhang YS(张郁松).Optimization of the extraction process of total flavonoids in sea buckthorn by orthogonal design.Seabuckthorn(沙棘),2007,20(1): 19-21.
20 Di DL(邸多隆),Liu YW(刘晔玮),Wang Q(王勤),et al.The extraction process of total flavonoids in seabuckthorn.J Chin Medic Mat(中药材),2006,29:979-981.
21 Li C(李辰).Performance of static adsorption and desorption of five macroporous resins for flavonoid aglycones in sea buckthorn leaves.Fin Chem(精细化工),2007,24:657-661.
22 Chen HF(陈海芳),Zhou WM(周文明),Fu JX(傅建熙),et al.Extracting technology of total flavonoids in leaf of Hippophae rhamnoides L.Acta Agri Boreali-Occid Sin (西北农业学报),2006,15 (1) :148-151
23 Chen C(陈雏),Zhang H(张浩),Xiao W(肖蔚).Study on the chemical constituents of Hippophae rhamnoides subsp. sinensis rousi.The Glob Seabuckthorn Res Dev(国际沙棘研究与开发),2005,3(4): 25-27.
24 Xu XY(徐晓云),Pang SY(潘思轶),Fu JZ(胡建中).Technology study on extracting proanthocynidins from sea buckthorn seed.Food Sci(食品科学),2005,26(3):165-169.
25 Jin HY(金海英).The extraction and the purification technical study of lowly the original anthocyanidin in the sea-buckthorn seed dregs. Seabuckthorn(沙棘),2005,18(2):29-31.
26 Wang XF(王翔飞),Zhou WM(周文明),Jian X(建熙),et al.Optimum conditions of extracting proanthocyanidins from seed of Hippophae rhamnoides L.Acta Agri Boreali-Occid Sin (西北农业学报), 2006,15 (3):204-207.
27 Zhou L(周力),Xie JC(谢建春),Ge YF(戈育芳),et al.The application of molecular imprinting technology for Hippophae rhamnoidse Linn. function integrants extraction. Acta Phy-chim Sin (物理化学学报),2002,18(9): 808-811.
28 Olsen J,Martin P,Wilson ID,et al.Methodology for assessing the properties of molecular imprinted polymers for solid phase extraction. Analyst,1999,124(4):467 -471.
29 Martin P,Wilson ID,Morgan DE,et al.Evaluation of a molecular imprinted polymer for use in solid phase extraction of propranolol from biological fluids.Anal Comm,1997,34(2):45-47.
30 Liao ZK(廖周坤),Xu Z(徐正).Supercritical fluid the extraction technical study of the total flavonoids in sea buckthorn by supercritical fluid.Sichuan Chem Corrosion Contl(四川化工与腐蚀控制),2003,6(6):1-3.
31 Zhu YG(祖元刚),Zhao JC(赵春建),Fu YJ(付玉杰).An orthogonal experiment to optimize ultrasonic extraction of flavonoids in Hippophae rhamnoides L.Chem Ind Forest Prod(林产化学与工业),2005,25(3): 85-88.
32 Geetha S,Sairam M,et al.Anti-oxidant and immunomodulatory properties of sea buckthorn (Hippophae rhamnoides L.) an in vitro study.J Ethnopharm.2002,79 (3):373-378.
33 Ma YM(马养民),Jiang SJ(姜少娟),Shi QH(史清华).Extraction and isolation of isorhamnetin and quercetin from marc of sea buckthorn fruit.J Northwest Forest Univ(西北林学院学报),2009,24 (5):121-124
34 Jiao X(焦翔),Yin LJ(殷丽君),Chen YQ(程永强).Extraction and antibacterial properties of flavonoids of seabuckthorn leaves.Food Sci(食品科学),2007,28(8):124-129.
35 Jiang SJ(姜少娟),Ma YM(马养民),Kong DL(孔东宁),et al.Research on ultrasonic wave extraction of total flavonoids from fruit marc of Hippophae rhamnoides L.J Northwest Sci-tech Univ Agric Forest (Nat Sci Ed)(西北农林科技大学学报(自然科学版)),2006,34(10):184-188.
36 Yang XH(杨喜花),Chen M(陈敏),Zhu L(朱蕾),et al.Supersonic circulation extraction of sea-buckthorn leaf total flavanone in sea-buckthorn leaf.Transac Chin Soc Agri Mach(农业机械学报),2006,37(3),166-168.
37 Fan XJ(樊兴君),You JM(尤进茂),Tan GZ(谭干祖),et al.Progress in microwave organic reaction enhancement.Prog Chem(化学进展),1998 (3):285-295.
38 Li XJ(李学坚),Huang HB(黄海滨).Extraction of clove oil by microwave.Guanxi J Tradi Chin Medic(广西中医药),2000,5 (3):49-50.
39 Ganglier K,Slag AA.Effective sample preparation method for extracting biologically active compounds from different matrices by microwave technique.J Chrom,1990,520:257-262.
40 Peng Y(彭游),Ye XL(叶兴琳),Deng ZY(邓泽元), et al.Tea saponin extraction by light wave without solvent and its application.Nat Prod Res Dev(天然产物研究与开发),2009,6:1023-1027.
41 Peng Y(彭游),Yin JM(尹健美).Extraction of flavone from seabuckthorn fruit residue by microwave irradiation. J Anhui Agri Sci(安徽农业科学),2010,38:3884-3885.
42 Yang XH(杨喜花),Chen M(陈敏),Zhang HJ(张华琚),et al.Microwave extraction of total flavonoids from Hippophae rhamnoides leaves.Chin Trad Herb Drugs(中草药),2006,37:535-537.
43 Zhao EL(赵二劳),Fan JF(范建凤),Zhang XY(张小燕).Enhancing of extraction of flavone from sea-buckthorn leaves by combining surfactant with microwave technology.Chin Surft Det Cosm (日用化学工业),2009,39(1):22-24.
44 Chen JE(陈金娥),Zhao LT(赵丽婷),Zhao EL(赵二劳),et al.Microwave extraction of flavonoids from Hippophae rhamnoides by orthogonal design. Chin Trad Patent Medi(中成药),2007,29:1612-1614.
45 Zhu HM(朱洪梅),Zhao M(赵猛),Wang WH(王文晖),et al.Extraction of flavonoids from seabuckthorn leaf by diseases.Agri Tech(农业与技术),2008,28(6):30-32.
46 Hajek T,Honys D,Capkovav.New method of plant mitochondria isolation and sub-fractionation for proteomic analyses.Plant Sci,2004,167:389-395.
47 Sezgintbrkm K,Dnckaya E.An amperometric inhibitor biosensor for the determination of reduced glutathione (GSH) without any derivatization in some plants. Biosens Bioelectr,2004,19(8):835-841.
48 Zhao CJ(赵春建),Zhu YG(祖元刚),Fu YJ(付玉杰),et al.Homogenated extraction of total flavonoids from fruits of sea buckthorn(Hippophae rhamnoides L.).Chem Ind Forest Prod(林产化学与工业),2006,26(2): 38-40.

[1]	张亚梅, 韩鸿萍, 宋道光. 响应面法优化暗紫贝母流浸膏提取工艺及其质量评价[J]. 天然产物研究与开发, 2024, 36(9): 1554-1563.
[2]	丁亚男, 王瑞阳, 高观祯, 汪惠勤, 周建武, 饶平凡. 油橄榄叶提取物对HaCaT细胞氧化损伤的保护作用及抑菌活性[J]. 天然产物研究与开发, 2024, 36(9): 1584-1591.
[3]	黄丽荣, 余佳, 李娇, 程莎骆衡. 基于网络药理学及实验验证探究苗药虎掌草不同溶剂提取物抗前列腺癌活性及其作用机制[J]. 天然产物研究与开发, 2024, 36(7): 1231-1241.
[4]	孔海军, 谌晓安, 李新龙. 沙棘黄酮对长期力竭运动大鼠心肌保护作用的机制研究[J]. 天然产物研究与开发, 2024, 36(6): 954-962.
[5]	盛蒙珂, 赵莹菲, 田若丹, 文春南, 刘淼, 麻兵继. 怀山药内生真菌Chaetomium sp.的次生代谢产物研究[J]. 天然产物研究与开发, 2024, 36(6): 982-985.
[6]	李百元, 张叶敏, 夏晶晶, 姜红宇, 曹林艳, 陈丹. 19种中药提取物对海洋致病溶藻弧菌生长和生物被膜的影响[J]. 天然产物研究与开发, 2024, 36(6): 1013-1021.
[7]	宋钰, 纪丽莲, 刘艳丽, 王桃云. 枸骨的化学成分及其药理活性研究进展[J]. 天然产物研究与开发, 2024, 36(6): 1082-1099.
[8]	李超, 刘云华, 秦登云, 黄志芳, 刘玉红, 陈燕, 易进海. 基于正交设计优化新鲜川芎中挥发油提取工艺[J]. 天然产物研究与开发, 2024, 36(5): 771-778.
[9]	张宏岐, 朱烈琴, 曾亚妮, 崔敏, 周莹霞, 杜娟. 忍冬木层孔菌多糖的提取工艺优化及其体外抗氧化活性研究[J]. 天然产物研究与开发, 2024, 36(4): 581-588.
[10]	邓超凡, 江志波, 马晓莉, 南泽东. 紫堇属植物苄基异喹啉类成分研究进展[J]. 天然产物研究与开发, 2024, 36(4): 694-716.
[11]	张一宁, 于志琪, 屈施旭, 刘同歌, 张玉红. 火麻叶中大麻二酚提取工艺的响应面法优化及不同部位含量分布[J]. 天然产物研究与开发, 2024, 36(3): 369-376.
[12]	邵林子, 程玉娇, 黄林华, 谈安群, 王华. 超声辅助深共晶溶剂高效提取枳实辛弗林的工艺优化及提取动力学分析[J]. 天然产物研究与开发, 2024, 36(3): 499-511.
[13]	宋丽娅, 李丽华, 毕思童. 基于网络药理学、分子对接技术及实验验证研究黄芪提取物治疗缺血缺氧性脑病的机制[J]. 天然产物研究与开发, 2024, 36(3): 520-527.
[14]	张闻婷, 杨旻静, 梅瑜, 王继华. 金线莲苷的研究现状[J]. 天然产物研究与开发, 2024, 36(2): 348-356.
[15]	吕福杰, 范在举, 李琦, 邓爱霞. 金果榄二萜类成分及其抗炎活性研究[J]. 天然产物研究与开发, 2024, 36(10): 1707-1713.