关键词: 棉毛橐吾, 化学成分, 倍半萜, 酚性化合物

Abstract: 18 compounds were isolated and purified from the rhizomes of Ligularia vellerea. Their structures were determined on the basis of the physiochemical properties and spectroscopy analysis as furanoeremophilan-14β,6α-olide (1), β-sitosterol (2),tiglic acid (3),palmitic acid (4),nonadecanoic acid methyl ester (5),eremophil-7-(11)-en-12,8α- (14β,6α)-diolide (6),8β-methoxyeremophil-7(11)-en-12,8α-(14β, 6α)-diolide (7),1-O-palmitoylglycerol (8),8β-hydroxyeremophil-7(11)-en-12,8α-（14β,6α）-diolide (9),p-hydroxycinnamic acid methyl ester (10),p-hydroxyacetophenone (11),umbelliferone (12),3,4-dihydroxyacetophenone1 (13),daucosterol (14),1,5-dicaffeoylquinic acid (15),p-hydroxycinnamic acid (16),caffeic acid (17),aesculetin (6,7-dihydroxycoumarin) (18).Compounds 4,5,8,10,13,15 and 17,18 are firstly obtained from Ligularia vellerea.

Key words: Ligularia vellerea, chemical constituents, sesquiterpenoids, phenolics