锁阳对运动训练大鼠睾酮含量、物质代谢及抗运动疲劳能力的影响

天然产物研究与开发 ›› 2014, Vol. 26 ›› Issue (1): 27-32.

锁阳对运动训练大鼠睾酮含量、物质代谢及抗运动疲劳能力的影响

郭伟1，曹建民2，周海涛3*

1 营口职业技术学院，营口115000；2 北京体育大学，北京100084；3 北京联合大学生物化学工程学院，北京100023

出版日期:2014-01-31 发布日期:2014-12-15

Effect of Cynomorium songarium Rupr on Testosterone Content,Substance Metabolism and Anti-fatigue Capacity of Rats After Exercise Training

GUO Wei1,CAO Jian-min2,ZHOU Hai-tao3*

1 Yingkou Vocational and Technical College,Yingkou 115000,China;2 Beijing Sport Universty,Beijing 100084,China;3 Biochemical Engineering College of Beijing Union University,Beijing 100023,China

Online:2014-01-31 Published:2014-12-15

摘要/Abstract

摘要： 本文以大强度耐力训练大鼠为模型，对锁阳对运动训练大鼠睾酮含量、物质代谢及抗运动疲劳能力的影响进行了研究。试验中分别以0.75、1.5、4.5 g/(kg.d)的剂量给大鼠灌胃49 d，并进行负重游泳实验、血睾酮等生化指标测定。结果显示，锁阳各剂量组力竭游泳时间长于运动对照组（T组）（P<0.01）；血清睾酮高于T组（P<0.01），血清皮质酮低于T组（P<0.05）；各组间血清睾酮与皮质酮比值变化与睾酮变化较为一致；肝糖原（P<0.05）、肌糖原（P<0.01）高于T组；血尿素氮低于T组（P<0.05）；血红蛋白高于T组（P<0.05）。从而表明补充锁阳可以减轻大鼠血睾酮、皮质酮受高强度运动量的影响，维持在正常生理水平；促进蛋白质合成，抑制氨基酸和蛋白质分解，提高血红蛋白含量和糖原的储备，增强抗疲劳能力，具有多靶点、多途径的显著特点。

关键词: 锁阳, 睾酮, 抗疲劳, 促黄体生成素, 促卵泡刺激素

Abstract: The objective of this study was to investigative the effect of Cynomorium songarium Rupr on the testosterone content,substance metabolism and anti-fatigue capacity in rats model.The rats were gavage with 0.75,1.5,4.5 g/(kg.d) doses of C.songarium. Weight-bearing swimming test was then carried out which was followed by the determination of serum testosterone and other biochemical indicators in 49 days.The results showed that exhaustive swimming time of C.songarium group was longer than that of motion control group (T group) (P<0.01).The content of serum testosterone of C.songarium group was higher than that of T group (P<0.01),but serum corticosterone was lower than that of the T group (P<0.05).The changes of content of serum testosterone were consistent with the changes of ratio of serum testosterone and corticosterone among different groups.The liver glycogen (P<0.05),muscle glycogen (P<0.01) and hemoglobin (P<0.05) in C.Songarium group were higher than these in T group,but the serum urea nitrogen were lower than the T group (P<0.05).The experimental results showed that the variances of testosterone and corticosterone content in serum caused by high-intensity exercise can be alleviated by C.songarium supplement to maintain the serum at normal physiological level.At the same time, C.songarium can promote protein synthesis,inhibit the decomposition of amino acids and proteins,increase the hemoglobin content and glycogen reserves.Hence,it showed the potential of anti-fatigue capability with multi-target,multi-channel features.

Key words: Cynomorium songarium Rupr, testosterone, anti-fatigue, luteinizing hormone, follicle-stimulating hormone

中图分类号:

R285.5

郭伟1，曹建民2，周海涛3*. 锁阳对运动训练大鼠睾酮含量、物质代谢及抗运动疲劳能力的影响[J]. 天然产物研究与开发, 2014, 26(1): 27-32.

GUO Wei1,CAO Jian-min2,ZHOU Hai-tao3*. Effect of Cynomorium songarium Rupr on Testosterone Content,Substance Metabolism and Anti-fatigue Capacity of Rats After Exercise Training[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2014, 26(1): 27-32.

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