关键词: 四瓣崖摩, 化学成分, 乙酰胆碱酯酶

Abstract: Fourteen compounds were isolated from the branches of Amoora tetrapetala and structurally identified by spectral analysis.The compounds were identified as 22ξ-hydroxytirucalla-7,24-dien-3,23-dione (1),dymacrin D (2),zeorin (3),α-spinasterol (4),8-hydroxy-6-methoxy-3-pentylisocoumarin (5),lichenxanthone (6),10-oxo-isodauc-3-en-15-al (7),(+)-ent-ficusol (8),3-methoxy-4-hydroxybenzoate (9),vanillin (10),methyl 2,4-hydroxy-3,6-dimethylbenzoate (11),methyl 2-hydroxy-4-methoxy6-propylbenzoate (12),methyl 2,4-dihydroxy-6-methylbenzoate (13) and methyl hydrogen succinate (14).All the compounds were isolated from this genus for the first time.All chemical constituents were tested for acetylcholinesterase inhibitory activity using the Ellman colorinetric method.The results indicated that compound 11 exhibited inhibitory activity against acetylcholinesterase.

Key words: Amoora tetrapetala, chemical constituents, acetylcholinesterase inhibitory activity