天然产物研究与开发 ›› 2018, Vol. 30 ›› Issue (3): 345-353.doi: 10.16333/j.1001-6880.2018.3.001

• 研究论文 •    下一篇

黑果枸杞化学成分研究

齐晶晶1,2,晏永明3,汪成祥4,程永现1,2,3*   

  1. 1云南中医学院,昆明 650500;2中国科学院昆明植物研究所 植物化学与西部植物资源持续利用国家重点实验室,昆明 650201;3深圳大学医学部药学院,深圳 518060,4青海大可生物科技有限公司,西宁 810000
  • 出版日期:2018-04-08 发布日期:2018-04-08

Compounds from Lycium ruthenicum

QI Jing-jing1,2, YAN Yong-ming3, WANG Cheng-xiang4, CHENG Yong-xian1,2,3*   

  1. 1Yunnan University of Traditional Chinese Medicine,Kunming 650500,China; 2State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,China; 3School of Pharmaceutical Sciences,Health Science Center,
    Shenzhen University,Shenzhen 518060,China; 4Qinghai Dake Biological Technology Co.Ltd.,Xining 810000,China
  • Online:2018-04-08 Published:2018-04-08

摘要: 采用色谱法从黑果枸杞中分离得到22个化合物,利用波谱学方法鉴定了它们的结构,分别鉴定为4-p-cumaroyl-α-L-rhamnosyl-(1→6)-β-D-glucose(1)、4-p-cumaroyl-α-L-rhamnosyl-(1→6)-α-D-glucose(2)、isosalipurposide(3)、咖啡酸乙酯(4)、trans-ferulic acid(5)、槲皮素3-O-β-D-芸香糖苷(6)、山柰酚-3-O-芸香糖苷(7)、水仙苷(8)、kaempferol 3-rutinoside-4′-glucoside(9)、柚皮素7-O-β-D-葡萄糖苷(10)、蛇葡萄素4′-O-β-D-吡喃葡萄糖苷(11)、helichrysin A(12)、柚皮素(13)、槲皮素(14)、东莨菪亭(15)、evofolin B(16)、(+)-isolariciresinol(17)、methyl-2,4-dihydroxy-5-methoxybenzoate(18)、3-甲氧基没食子酸(19)、4-acetyl-2,6-dimethoxyphenol(20)、香草乙酮(21)和苯甲酸甲酯(22)。其中化合物1为新化合物,化合物2、3、9、11、12 和16~19均为首次从本属中被分离得到。

关键词: 黑果枸杞, 茄科, 黄酮, 黄酮苷

Abstract: Twenty two compounds were isolated from the fruits of Lycium ruthenicum Murr. Their structures were identified as 4-p-cumaroyl-α-L-rhamnosyl-(1→6)-β-D-glucose(1),4-p-cumaroyl-α-L-rhamnosyl-(1→6)-α-D-glucose (2),isosalipurposide (3),ethyl caffeate (4),trans-ferulic acid (5),quercetin 3-O-β-D-rutinoside (6),kaempferol-3-O-rutinoside (7),isorhamnetin 3-rutinoside (8),kaempferol 3-rutinoside-4′-glucoside (9),naringenin 7-O-β--D-glucopyranoside (10),ampelopsin 4′-O-β--D-glucopyranoside (11),helichrysin A (12),naringenin (13),quercetin (14),scopoletin (15),evofolin B (16),(+)-isolariciresinol (17),methyl-2,4-dihydroxy-5-methoxybenzoate (18),3-O-methylgallic acid (19),4-acetyl-2,6-dimethoxyphenol (20),acetovanillone (21) and methyl benzoate (22),respectively,by spectroscopic methods.Compound 1 is a new substance.In addition,compounds 2,3,9,11,12,and 16-19 were isolated from the genus Lycium for the first time.

Key words: Lycium ruthenicum, Solanaceae, flavonoids, flavonoidal glycosides

中图分类号: 

R93