天然产物研究与开发 ›› 2020, Vol. 32 ›› Issue (增刊1): 153-161.doi: 10.16333/j.1001-6880.2020.S.025

• 综述 • 上一篇    下一篇

忧遁草化学成分及应用研究进展

杨懋勋1,2*，陈河如3，曹文强1，赵柏松1,4   

  1. 1珠海大横琴科技发展有限公司；2珠海霍普金斯医药研究院股份有限公司，珠海 519000；3暨南大学药学院，广州 510632；4珠海希望基因医药研究院有限公司，珠海 519000

  • 出版日期:2020-06-28 发布日期:2020-07-21
  • 基金资助:
    中国博士后科学基金（2019M663360）；暨南大学横向合作研究项目

Study progress on chemical constituents and application of Clinacanthus nutans

YANG Mao-xun1,2*,CHEN He-ru3,CAO Wen-qiang1,ZHAO Bai-song1,4   

  1. 1Zhuhai Hopegenes Medical & Pharmaceutical Institute Co.,Ltd.; 2Zhuhai Da Hengqin Science and Technology Development Co.,Ltd.,Zhuhai 519000,China;3College of Pharmacy,Jinan University,Guangzhou 510632,China; 4Zhuhai Hopegenes Chinese Medicine Institute Co.,Ltd.,Zhuhai 519000,China

  • Online:2020-06-28 Published:2020-07-21

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摘要： 忧遁草是闻名于东南亚各国及我国海南、广东、广西等南部地区的传统药用植物及食用野菜，具有抗肿瘤、抗氧化、免疫调节、抗炎、降血糖等广泛的药理活性。研究发现，忧遁草有多种生物活性化学成分，萜类化合物、甾体类化合物、糖苷类化合物是研究较多和较深入的代表性化合物，近年来新发现骈双四氢呋喃型木脂素等类型的活性化合物。在专利技术研究应用方面，忧遁草在药品食品中的应用一直是科研人员主要关注和成果比较集中的领域，在化妆品日化品、动物饲料、工艺技术等方面的研究开发也逐渐增多。本文对国内外忧遁草化学成分的研究论文及其国内专利技术研究应用进行综述，为阐明忧遁草的药效物质基础提供参考，为忧遁草资源的开发利用提供科学依据。


关键词: 忧遁草, 化学成分, 药用研究, 食用研究, 研究进展

Abstract:

Clinacanthus nutans (Burm.f.) Lindau is a well-known traditional herb and vegetable in Southeast Asia countries and Hainan, Guangdong, Guangxi and other southern regions of China,with comprehensive pharmacological activities such as anticancer,antioxidation,immuno-regulation,anti-inflammatory,α-glucosidase inhibitory and so on.C. nutans contains various bioactive constituents,among which terpenoids,steroids and glucosides are representative compounds with more and further study,and furofuran lignans are new-found bioactive constituents.In patent application,for the most reported achievements,medical and edible application is always focused by researchers,in the meantime,applications in cosmetics and daily chemicals,animal feed and process technology were also gradually increased.To provide a reference for pharmacodynamic constituents in C. nutans and a scientific basis for further development and application of C. nutans resource,the research progress of chemical constituents at home and abroad and patent application related to C. nutans in China were reviewed in the current paper.

Key words: Clinacanthus nutans, chemical constituents, medical application, edible application, research progress

中图分类号:  R284

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