Effect of Acanthopanax giraldii Harms Polysaccharide on Enzyme Activity of THP-1 Macrophage

doi:10.16333/j.1001-6880.2016.5.018

Abstract

Abstract: To observe the effect of Acanthopanax giraldii Harms polysaccharide(AHP-II) on enzyme activities of THP-1 macrophages,macrophages converted from THP-1 monocytes by PMA,were incubated with different doses of AHP-II for 48 h.The activities of superoxide dismutase(SOD),succinodehydrogenase(SDH),acid phosphatase(ACP),lysozyme(LZM) and ATPase were determined. The results showed that the activities of SOD,SDH,ACP,LZM and ATPase were significantly enhanced,possibly demonstrating that AHP-II can enhance immunomodulatory effects of THP-1 macrophages.

Key words: Acanthopanax giraldii Harms polysaccharide, macrophage, SOD, SDH, ACP, LZM, ATPase

CLC Number:

R392.5

CAI Wen-di1,CHEN Yong1*,CHEN Zhi-ting2,XU Zhi-lu2,FU Xiao-yan1. Effect of Acanthopanax giraldii Harms Polysaccharide on Enzyme Activity of THP-1 Macrophage[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2016, 28(5): 741-744.

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Effect of Acanthopanax giraldii Harms Polysaccharide on Enzyme Activity of THP-1 Macrophage

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