Piceatannol is a kind of nature small molecule compound with a chemical structure similar to resveratrol.It has many bioactivities,including but not limited to:antioxidant,scavenging free radicals,antibacterial,anti-inflammatory,anti-leukemia,anti-cell proliferation,improving the ability of immune regulation,anti-cancer,prevention of cancer and so on.By comparing with resveratrol,piceatannol is stronger than resveratrol in aspects of biological activities about anti-oxidation and anti-invasion perspectine.However,the antitumor mechanism of piceatannol has not been clarified yet.For the past few years,piceatannol has attracted more and more attention in aspects of inhibiting tumor cell proliferation,inducing tumor cell apoptosis,and inhibiting tumor cell invasion ability and migration ability.It is scientific paper and journal has summarized the antitumor effect mechanism of piceatannol referenced based on the latest research to piceatannol.This paper is to afford a theoretical foundation and experimental basis for further development of piceatannol into use of antitumor drugs.