Glycoprotein is a type of binding protein formed by covalently connecting oligosaccharides and polypeptide chains,which is widely present in variety,and have significant therapeutic and health care effects,such as anti-oxidation,anti-tumor and immune regulation,etc.In this paper,the studies of extraction,isolation and purification,structure identification and pharmacological actions of glycoproteins of Chinese materia medica in recent years are summarized,to discuss whether glycoproteins can be used as one of the material bases for Chinese materia medica to exert its efficacy and be further developed and applied.