Exercise-induced asthma (EIA) is one of the most frequent chronic diseases among athletes and is gaining increasing concern.The pathological mechanisms and pharmacology-based treatments of EIA have been widely studied and some progress has been made,however,long-term using EIA drugs would induce health-related side effects and even doping violations.Thus,a safe,healthy and effective alternative of traditional treatment methods is particularly required.Tangeretin extracted from a natural citrus was recently reported to show great promise in EIA treatment.Therefore,the current article specifically reviewed the biological activities of tangeretin referring to anti-inflammatory,antioxidant,anti-cancer,regulation of uric acid and cortisol secretion,regulation of glucolipid metabolism and anti-obesity,neuroprotection.It would provide ideas and theoretical support for further studying and developing tangeretin-based food,healthcare products or drugs in EIA treatment.