Abstract: Fourteen compounds were isolated from the ethanol extract of Chinese herbal medicine Scrophularia ningpoensis Hemsl., which were identified as sugiol (1), β-sitosterol (2), lupaneol (3), ursolic acid (4), Rhamnose (5), daucosterol (6), sucrose (7), caffeic acid (8), oleic acid (9), 3-O-(6′-O-palmitoyl-β-D-glucosyl)-spinasta-7,22-diene (10), clematomanshurica saponin E (11), α-caryphy (12), α-cedrol (13), and scrophuloside A4 (14) on the basis of physicochemical and spectroscopic evidences. Compounds 3, 5, and 8-14 were isolated from this plant for the first time.

Key words: Scrophularia ningpoensis Hemsl., Scrophularia L., chemical constituents