Abstract: The paper provided a process for preparing zeaxanthin from lutein by basis catalysis. The process also included optimization of technic parameters. The results showed that the optimal reaction condition was as follows: using 1, 2-propanediol as solvent, reaction time for 168 h and reaction temperature at 110 ℃, under inert atmosphere. The ratio of 1, 2-propanediol to lutein was 20, and the ratio of potassium hydroxide to lutein was 6. According to HPLC analysis, the yield of zeaxanthin can reach 93% under the optimal condition.

Key words: lutein, zeaxanthin, carotenoids, isomerization