天然产物研究与开发 ›› 2015, Vol. 27 ›› Issue (11): 1843-1846.doi: 10.16333/j.1001-6880.2015.11.001

• 研究论文 •    下一篇

长序三宝木中的降二萜成分研究

唐贵华1,2,苑春茂1,张于1,李顺林1,邸迎彤1*,郝小江1*   

  1. 1 中国科学院昆明植物研究所 植物化学与西部植物资源持续利用国家重点实验室,昆明 650201;2 中山大学药学院,广州 510006
  • 出版日期:2015-11-30 发布日期:2015-12-02

Degraded Diterpenoids from Trigonostemon howii

TANG Gui-hua1,2, YUAN Chun-mao1, ZHANG Yu1, LI Shun-lin1, DI Ying-tong1*, HAO Xiao-jiang1*   

  1. 1 State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences, Yunnan Kunming 650201,China;2 School of Pharmaceutical Sciences,Sun Yat-sen University,Guangdong Guangzhou 510006,China
  • Online:2015-11-30 Published:2015-12-02

摘要: 从长序三宝木(Trigonostemon howii)茎的化学成分研究中发现4个降二萜化合物,其中新化合物trigohowilone A(1)经波谱数据包括核磁、质谱、比旋光等鉴定为trigoxyphin P的对映异构体。已知化合物结构确定为trigoxyphin Q(2),trigohowilol H(修订后的俗名)(3)和9-O-demethyltrigonostemone(4)。所有化合物均为首次从该植物中分离得到。

关键词: 大戟科, 长序三宝木, 降二萜, trigohowilone A, (-)-trigoxyphin P

Abstract: Phytochemical investigation on the stems of Trigonostemon howii resulted in the isolation of four degraded diterpenoids.A new compound,trigohowilone A (1), was defined as the enantiomer of trigoxyphin P based on the analyses of its spectroscopic data including NMR,MS,and the specific rotation data.The structures of known compounds were identified as trigoxyphin Q (2),trigohowilol H (revised trivial name) (3),and 9-O-demethyltrigonostemone (4). All compounds were obtained from the plant for the first time.

Key words: Euphorbiaceae, Trigonostemon howii, degraded diterpenoids, trigohowilone A, (-)-trigoxyphin P

中图分类号: 

R284.1 Q946.91