天然产物研究与开发 ›› 2016, Vol. 28 ›› Issue (10): 1520-1525.doi: 10.16333/j.1001-6880.2016.10.004

• 研究论文 • 上一篇    下一篇

粘叶莸的化学成分研究

罗国勇1,2,郎天琼1,周敏2,刘燕2,罗应刚2*,张国林2*   

  1. 1 贵阳中医学院药学院,贵阳 550025;2 中国科学院成都生物研究所,成都 610041
  • 出版日期:2016-10-31 发布日期:2017-03-30

Chemical Components from Caryoptesis glutinosa

LUO Guo-yong1,2,LANG Tian-qiong1,ZHOU Min2,LIU Yan2,LUO Ying-gang2*,ZHANG Guo-lin2*   

  1. 1 College of Pharmacy,Guiyang College of Traditional Chinese Medicine,Guiyang 500025,China; 2 Chengdu Institute of Biology,Chinese Academy of Sciences,Chengdu 610041,China
  • Online:2016-10-31 Published:2017-03-30

摘要: 综合利用多种色谱方法从粘叶莸(Caryopteris glutinosa)的乙醇提取物中分离得到13个化合物,并通过多种波谱学手段鉴定它们的结构分别为:caryopterpene J(1)、5-羟基-7,3′,4′-三甲氧基黄酮(2)、5-羟基-7,8,4′-三甲氧基黄酮(3)、5-羟基-7,4′-二甲氧基黄酮(4)、8-甲氧基芹菜素(5)、5,4′-二羟基-7,8,3′-三甲氧基黄酮(6)、5,4′-二羟基-7,8-二甲氧基黄酮(7)、5-羟基-7,8,3′,4′-四甲氧基黄酮(8)、acteoside(9)、N-trans-feruloyl 3-O-methyldopamine(10)、secoisolariciresinol(11)、isolariciresinol(12)和dehydroconiferyl alcohol(13)。其中,化合物1为新化合物,其它化合物除9以外均为首次从莸属植物中分离得到。

关键词: 粘叶莸, 环烯醚萜, 木脂素, 化学成分, 马鞭草科

Abstract: Thirteen compounds were obtained from the ethanol extract of Caryopteris glutinosa by applying various chromatographic methods.Their structures were elucidated and identified as caryopterpene J (1),5-hydroxy-7,3′,4′-trimethoxyflavone (2),5-hydroxy-7,8,4′-trimethoxyflavone (3),5-hydroxy-7,4′-dimethoxyflavone (4),8-methoxyapigenin (5),5,4′-dihydroxy-7,8,3′-trimethoxyflavone (6),5,4′-dihydroxy-7,8-dimethoxyflavone (7),5-hydroxy-7,8,3′,4′-tetramethoxyflavone (8),acteoside (9),N-trans-feruloyl-3-O-methyldopamine (10),secoisolariciresinol (11),isolariciresinol (12) and dehydroconiferyl alcohol (13),respectively,based on the spectral data.Among them,compound 1 was a new compound.The rest compounds excluding 9 were obtained from Caryopteris genus for the first time.

Key words: Caryopteris glutinosa, iridoids, lignans, chemical composition, Verbenaceae

中图分类号: 

R284.2