天然产物研究与开发 ›› 2017, Vol. 29 ›› Issue (1): 74-78.doi: 10.16333/j.1001-6880.2017.1.013

• 研究简报 • 上一篇    下一篇

天山假狼毒地上部分化学成分研究

石磊岭1,郭宝林2,李广志2,贾晓光1,古丽娜·沙比尔1,斯建勇2*   

  1. 1 新疆维吾尔自治区中药民族药研究所,乌鲁木齐 830002;2中国医学科学院药用植物研究所,北京 100193
  • 出版日期:2017-01-31 发布日期:2017-02-17

Chemical Constituents from the Aerial Parts of Stelleropsis tianschanica Pobed.

SHI Lei-ling1,GUO Bao-lin2,LI Guang-zhi2,JIA Xiao-guang1,GULINAR Sabir1 ,SI Jian-yong2*   

  1. 1 Xinjiang Institute of Chinese and Ethnic Medicine,Urumqi 830002,China; 2 Institute of Medicinal Plant Development,Peking Union Medical College and Chinese Academy of Medical Sciences,Beijing 100193,China
  • Online:2017-01-31 Published:2017-02-17

摘要: 综合运用硅胶柱色谱、Sephadex LH-20凝胶柱色谱及制备型高效液相等分离技术,结合化合物理化性质及其波谱数据等多种结构鉴定手段对天山假狼毒地上部分进行化学成分研究。最终,从天山假狼毒地上部分分离鉴定得到了16个化合物,分别为:西瑞香素(1)、西瑞香素-7-O-β-D-葡萄糖苷(2)、繸状芸香甙酯(3)、9′-甲氧基繸状芸香甙酯(4)、7,7′-二羟基-6,8′-双香豆素(5)、Bicoumol-7′-O-β-glucopyranoside(6)、7,8-二羟基香豆素(7)、genkwanol B(8)、Viburnolide A(9)、对羟基苯甲酸(10)、白桦脂醇(11)、胡萝卜苷(12)、β-谷甾醇(13)、正二十四烷醇(14)、正二十三烷醇(15)、正三十五烷醇(16)。化合物1~16均为首次从假狼毒属植物中分离得到。

关键词: 瑞香科, 假狼毒属, 天山假狼毒, 化学成分, 双香豆素类

Abstract: The chemical constituents of Stelleropsis tianschanica were separated and purified by various chromatographic methods and identified by spectroscopic data.Sixteen compounds were obtained,and identified as daphnoretin (1),daphnoretin-7-O-β-D-glucoside (2),rutarensin (3),9′-methoxyl rutarensin (4),7,7′dihydroxy-2H,2′H-6,8′-bichromene-2,2′-dione (5),bicoumol-7′-O-β-glucopyranoside (6),7,8-dihydroxy coumarin (7),genkwanol B (8),viburnolide A (9),4hydroxybenzyl alcohol (10),botulin (11),daucosterol (12), β-sitosterol (13),tetracosanol (14),tricosanol (15),1-pentatriacontano (16).Compounds 1-16,were all obtained from the genus Stelleropsis for the first time.

Key words: Thymelaeacea, Stelleropsis, Stelleropsis tianschanica pobed., chemical constituents, bicoumarin

中图分类号: 

R979.1