天然产物研究与开发 ›› 2017, Vol. 29 ›› Issue (4): 543-548.doi: 10.16333/j.1001-6880.2017.4.001

• 研究论文 •    下一篇

密花荚蒾中两个新的环烯醚萜

杨惠1,2,丁林芬1,涂文超1,2,吴兴德2*,宋流东1*   

  1. 1 昆明医科大学 药学院暨云南省天然药物药理重点实验室,昆明 650500;2 中国科学院昆明植物研究所 植物化学与西部资源持续利用国家重点实验室,昆明 650201
  • 出版日期:2017-04-29 发布日期:2017-05-08

Two New Iridoids from Viburnum congestum

YANG Hui1,2,DING Lin-fen1,TU Wen-chao1,2,WU Xing-de2*,SONG Liu-dong1*   

  1. 1 School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products,Kunming Medical University,Kunming 650500,China;2State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,China
  • Online:2017-04-29 Published:2017-05-08

摘要: 利用现代色谱分离手段,从荚蒾属植物密花荚蒾(Viburnum congestum)枝叶的95%乙醇提取物中分离得到15个化合物,根据理化性质及现代波谱技术鉴定其结构为密花荚蒾甲素(1)、密花荚蒾乙素(2)、adoxoside(3)、2′-(E)-p-coumaroyldihydropenstemide(4)、3β,23-二羟基-乌苏烷-12-烯-28-酸(5)、ilelatifol A(6)、11-oxoerythrodiol(7)、花旗松素(8)、儿茶素(9)、表儿茶素(10)、表儿茶素-[7,8-bc]-4β-(4-羟基苯)-二氢-2(3H)-吡喃酮(11)、东莨菪素(12)、对羟基苯甲酸甲酯(13)、(E)-对香豆酸乙酯(14)、(E)-对香豆酸(15)。其中,化合物1和2为新化合物,化合物5、6、11、12为首次从荚蒾属植物中分离得到。

关键词: 忍冬科, 荚蒾属, 密花荚蒾, 化学成分, 环烯醚萜

Abstract: Fifteen compounds were isolated from the twigs and leaves of Viburnum congestum by various chromatographic methods.Their structures were identified as viburcongestin A(1),viburcongestin B(2),adoxoside(3),2′-(E)-p-coumaroyldihydropenstemide(4),3β,23-dihydroxyurs-12-en-28-oic acid(5),ilelatifol A(6),11oxoerythrodiol(7),taxifolin(8),catechin(9),epicatechin(10),epicatechin-(7,8-bc)-4β-(4-hydroxyphenyl)-dihydro-2(3H)-pyranone(11),scopoletin(12),methylparaben(13),(E)-p-coumarinic acid ethyl ester(14),(E)-p-coumarinic acid(15),respectively,based on spectroscopic methods,including ESI-MS,1H and 13C NMR,IR,and UV techniques.Among them,compounds 1 and 2 were new compounds and compounds 5,6,11,and 12 were isolated from Viburnum genus for the first time.

Key words: Caprifliaceae, Viburnum, Viburnum congestum, chemical constituents, iridoids

中图分类号: 

R284.1