关键词: 桑叶, 化学成分, 紫罗兰酮类化合物

Abstract: The chemical constituents of Morus alab L.were isolated by column chromatography on silica gel,Rp-18,Sephadex LH-20 and prep-HPLC by chemical and spectral analyses.Eighteen compounds were finally isolated and purified from the leaves of Morus alab L..Their structures were elucidated as (3R)-3-hydroxy-β-ionone (1),(6S,7E,9S)-9-hydroxy-megastigma-4,7-dien-3-one (2),dehydrovomifol (3),(3S,9R)-3-hydroxy-7,8-didehydro-β-ionol 9-O-β-D-glucopyranoside (4),(6R,9R)-3-oxo-α-ionol 9-O-β-D-glucopyranoside (5),(E)-6-［9-(β-D-glucopyranosyloxy) butyl-idene］-1,1,5-trimethyl-4-cyclohexen-3-one (6),(Z)-6-［9-(β-D-glucopyranosyloxy)buty-lidene］-1,1,5-trimethyl-4-cyclohexen-3-one (7),(6S,9S)-3-oxo-β-ionol 9-O-β-D-glucopyranoside (8),blumenol C 9-O-β-Dglucopyranoside (9),lcariside B1 (10),(3S)-O-β-D-glucopy ranosyl-6-［3-oxo-(2S)-butenylidenyl］-1,1,5-trimethylcyclohexan-(5R)-ol (11),(E)-4-((1S,3R,4R)-1-hydroxy-4,5,5-trimethyl-7-oxabicyclo［4.1.0］-heptan-1-yl)but-1-en-3-one (12),(6R,9S)-vomifoliol-9-O-β-apiofuranosyl-(1′′→6′)-O-β-glucopyranoside (13),(9R)-hydroxy-(10E,12Z,15Z)-octadecatrienoic acid (14),(2E)-dodecenedioic acid (15),2,5-dihydro-5-oxo-5-furanoctanoic acid (16),1-glyceryl linolenate (17),ndotfiacontanol (18)。Compounds 1-18 were obtained from this plant or the first time.

Key words: Morus alab L., chemical constituents, ioone derivatives