天然产物研究与开发 ›› 2019, Vol. 31 ›› Issue (2): 354-362.doi: 10.16333/j.1001-6880.2019.2.027

• 综述 • 上一篇    下一篇

蛋白水解物制备工艺及其在生物技术领域中的应用研究进展

张邵博1,2,靳冬武3,李明生1,2*   

  1. 1西北民族大学生命科学与工程学院;2甘肃省动物细胞工程技术研究中心;3兰州民海生物工程有限公司,兰州 730030
  • 出版日期:2019-03-07 发布日期:2019-03-07
  • 基金资助:

    甘肃省科技计划(17YF1WA166);甘肃省科技计划(1504WKCA094);科技部科技援助项目(KY201501005);中国-马来西亚清真食品国家联合实验室开放基金(CM2017001)

Research progress of preparation process of protein hydrolysates and its application in biotechnology fields

ZHANG Shao-bo1,2,JING Dong-wu3,LI Ming-sheng1,2*   

  1. 1Life Science and Engineering College of Northwest University for Nationalities; 2Engineering Technology Research Center for Animal Cell; 3Lanzhou MinHai Bio-Engineering Co.,Ltd,Lanzhou 730030,China
  • Online:2019-03-07 Published:2019-03-07

摘要: 蛋白水解物是蛋白质经酶、酸、碱和发酵等方法水解得到的混合物,由于其含有丰富的氨基酸和多肽,并为细胞生长提供多种营养成分、贴壁因子及生长因子类似物等,从而在生物技术领域中得到了广泛的应用。本文综述了蛋白水解物制备工艺、在生物技术领域中的应用及其在细胞培养中对细胞增殖、代谢的影响,以期为蛋白水解物的开发和应用提供参考。

关键词: 蛋白水解物, 制备工艺, 生物领域, 细胞培养, 应用

Abstract: Protein hydrolysates,a mixture of amino acids and peptides,were prepared through the hydrolysis of proteins by enzyme,acid,alkali and fermentation methods.Protein hydrolysates had been widely used in the field of biotechnology due to that the hydrolyzatescould provide a variety of nutrients,adherent factors and growth factor analogs for cell growth.This review summarized the preparation of protein hydrolysates,the application of hydrolysates in the field of biotechnology,and the effects of hydrolysates on cell culture,proliferation and metabolism in order to provide basis for the further study and application of protein hydrolysates.

Key words: protein hydrolysates, preparation process, application in biotechnology fields, cell culture

中图分类号: 

Q816 R915