天然产物研究与开发 ›› 2023, Vol. 35 ›› Issue (2): 332-341.doi: 10.16333/j.1001-6880.2023.2.017

• 综述 • 上一篇    下一篇

中药气味的化学成分检测及物质基础研究进展

张三妹,吴   梅,吴   飞*,冯   怡*   

  1. 上海中医药大学 中药现代制剂技术教育部工程研究中心,上海 201203
  • 出版日期:2023-02-28 发布日期:2023-03-02
  • 基金资助:
    上海市卫健委科研基金(201940296,202140347)

Research progress on chemical composition detection and substance basis of odor of traditional Chinese medicine

ZHANG San-mei1,WU Mei,WU Fei*,FENG Yi*   

  1. Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine,Ministry of Education,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China
  • Online:2023-02-28 Published:2023-03-02

摘要: 气味是中药的重要感官指标,与中药品质及药效作用直接相关。一些常用中药具有特殊的气味,也是其鉴别和品质评价的重要指标。从化学物质基础角度来说,挥发性化学成分的种类和含量差异,导致了不同中药气味的异同。研究中药气味的化学物质基础对中药的综合质量控制、临床应用辅助、科学内涵解释等中药现代研究具有重大意义,而目前阶段对中药气味的研究,主要集中在挥发油的成分、制剂工艺和药理作用方面,以及使用感官分析设备对中药气味进行现代表征和区分,而对中药气味的分类和化学物质基础尚未有较为系统的总结和介绍。本文从中药气味检测技术、气味的感官分类、气味的化学物质基础和中药制剂生产过程中气味的变化规律等方面对此主题进行综述,并对其研究方向进行展望。

关键词: 中药气味, 化学物质基础, 感官评价, 检测技术

Abstract:

The odor of traditional Chinese medicine(TCM)is an important sensory function directly related to the quality and efficacy of TCM.Special odor is also an important indicator for the identification and quality evaluation of TCM.From the perspective of chemical basis,volatile ingredients are different and Chinese medicine odor different.Studying the chemical substance basis of TCM odor is of great significance to the modern research of TCM,such as comprehensive quality control,clinical application assistance and scientific connotation interpretation of traditional Chinese medicine.At present,the research on TCM odor mainly focuses on the composition,preparation technology and pharmacological function of volatile oil,as well as the modern characterization and differentiation of TCM odor by using sensory analysis equipment.However,there is no systematic summary and introduction on the classification of TCM odor and the basis of chemical substances.This paper summarizes this topic from the aspects of odor detection technology,sensory classification of odor,chemical material basis of odor and variation law of odor during the production of TCM preparations,and looks forward to its research direction.

Key words: traditional Chinese medicine odor, chemical material basis, sensory evaluation, determination technology

中图分类号:  R284.1