天然产物研究与开发 ›› 2024, Vol. 36 ›› Issue (12): 2159-2179.doi: 10.16333/j.1001-6880.2024.12.016 cstr: 32307.14.1001-6880.2024.12.016

• 综述 • 上一篇    

野桐属植物的化学成分及药理活性研究进展

张高荣，陈兰燕，李   俊*，赖红芳*   

  1. 1河池学院化学与生物工程学院 广西蚕桑生态学与智能化技术应用重点实验室 广西现代蚕桑丝绸协同创新中心，河池 546300；2广西师范大学化学与药学学院 省部共建药用资源化学与药物分子工程国家重点实验室，桂林 541004；3河池学院化学与生物工程学院 微生物及植物资源开发利用广西高校重点实验室，河池 546300
  • 出版日期:2024-12-26 发布日期:2024-12-26
  • 基金资助:
    国家自然科学基金（32060097）；广西高校中青年教师科研基础能力提升项目（2022KY0611）；河池学院高层次人才项目（2021GCC018）；广西大学生创新创业计划（20231060543）

Research progress on chemical constituents and pharmacological activities of plants from Mallotus Lour.

ZHANG Gao-rong1,2,3,CHEN Lan-yan1,3,LI Jun1,2*,LAI Hong-fang1,3*   

  1. 1Guangxi Key Laboratory of Sericulture Ecology and Applied Intelligent Technology,Guangxi Collaborative Innovation Center of Modern Sericulture and Silk,School of Chemistry and Bioengineering,Hechi University,Hechi 546300,China;2State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources,School of Chemistry and Pharmaceutical Sciences,Guangxi Normal University,Guilin 541004,China;3Guangxi Colleges Universities Key Laboratory of Exploitation and Utilization of Microbial and Botanical Resources,School of Chemistry and Bioengineering,Hechi University,Hechi 546300,China
  • Online:2024-12-26 Published:2024-12-26

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摘要： 野桐属（Mallotus Lour.）植物属于大戟科，全球约有140种，主要分布在热带和亚热带地区。我国野桐属植物资源丰富，该属植物在我国分布有36种。该属中的多种植物常用作传统药物使用，研究表明其含有多种化学成分，主要包括萜类、甾体类、黄酮类、香豆素类、酚类、苯并吡喃类及其他类，具有抗菌、抗炎、抗癌、抗氧化、保肝、抗抑郁、抗虫及保护神经等多种药理活性。本研究对近10年来的野桐属植物的化学成分及药理活性研究进行综述，以期为野桐属植物资源的进一步开发利用提供理论依据。

关键词: 野桐属, 化学成分, 药理活性, 抗炎, 抗癌, 抗菌

Abstract:

Mallotus Lour.,belonging to Euphorbia family,consists about 140 species in the world and mainly distributes in tropical and subtropical regions.The resources of plants from Mallotus Lour. are very rich in China,36 species of which can be found in southern and south-west China.The application of Mallotus species in traditional Chinese medicine has a long history.Phytochemical investigations have shown that the plants from Mallotus Lour. contain a variety of chemical components,mainly including terpenoids,steroids,flavonoids,coumarins,phenols,benzopyranes and other classes,which have antibacterial,anti-inflammatory,anticancer,antioxidant,hepatoprotective,anti-depression,anti-insect,nerve protection and other pharmacological activities.The new development of constituents and pharmacological activities of Mallotus Lour.in the past ten years were reviewed and summarized for providing a theoretical basis for the further development and utilization of the resources of Mallotus Lour..

Key words: Mallotus Lour., chemical constituent, pharmacological activities, anti-inflammation, anti-cancer, antibacterial

中图分类号:  R284 R285

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