中医药治疗血管性痴呆的研究进展

doi:10.16333/j.1001-6880.2025.10.017

天然产物研究与开发 ›› 2025, Vol. 37 ›› Issue (10): 1962-1973.doi: 10.16333/j.1001-6880.2025.10.017 cstr: 32307.14.1001-6880.2025.10.017

中医药治疗血管性痴呆的研究进展

罗钦哲,廖玉圆,李娟*,李顺祥*

湖南中医药大学药学院湖南省中药活性物质筛选工程技术研究中心湖南省中美老年性退行性疾病治疗药物国际联合研究中心,长沙 410208

出版日期:2025-10-31 发布日期:2025-10-30
基金资助:
湖南省科技厅重点研发计划(2023SK2048,2021CB1 012)；湖南中医药大学重点学科中药学科(校行发规字［2023］2号)

Research progress of traditional Chinese medicine in treating vascular dementia

LUO Qin-zhe,LIAO Yu-yuan,LI Juan*,LI Shun-xiang*

School of Pharmacy,Hunan University of Chinese Medicine;Hunan Engineering Technology Research Center for Bioactive Substance Discovery of Chinese Medicine;Hunan Province Sino-US International Joint Research Center for Therapeutic Drugs of Senile Degenerative Diseases,Changsha 410208,China

Online:2025-10-31 Published:2025-10-30

摘要/Abstract

摘要：

血管性痴呆(vascular dementia,VaD)是由脑血管疾病导致的认知障碍综合征。中医认为VaD与玄府郁闭、五脏虚衰等有关。现代医学主要将VaD与脑小血管病、动脉粥样硬化、遗传基因等机制相联系。近年来,中医治疗VaD的方法,包括中药复方、外治法以及中西医结合治疗等,显示出越来越高的疗效。本文通过归纳这些治疗方法的调控机制,为VaD的临床治疗提供理论基础。

关键词: 血管性痴呆, 中医药治疗, 发病机制, 中药复方, 中西医结合治疗

Abstract:

Vascular dementia (VaD) is a clinical syndrome caused by cerebrovascular disease.Traditional Chinese medicine believes that VaD is related to the stagnation of Xuanfu and the deficiency of the five internal organs.Modern medicine mainly associates VaD with mechanisms such as cerebral small vessel disease,atherosclerosis,and genetic genes.In recent years,the methods of traditional Chinese medicine in the treatment of VaD,including traditional Chinese medicine compound,external treatment and integrated traditional Chinese and Western medicine treatment,have shown increasing efficacy.This article provides a theoretical basis for the clinical treatment of VaD by summarizing the regulatory mechanisms of these treatment methods.

Key words:

"> vascular dementia, traditional Chinese medicine treatment, pathogenesis, traditional Chinese medicine compound, integrated traditional Chinese and Western medicine treatments

中图分类号: R277.7

罗钦哲, 廖玉圆, 李娟, 李顺祥. 中医药治疗血管性痴呆的研究进展[J]. 天然产物研究与开发, 2025, 37(10): 1962-1973.

LUO Qin-zhe, LIAO Yu-yuan, LI Juan, LI Shun-xiang. Research progress of traditional Chinese medicine in treating vascular dementia[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2025, 37(10): 1962-1973.

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中医药治疗血管性痴呆的研究进展

Research progress of traditional Chinese medicine in treating vascular dementia

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