新体系下茴脑臭氧化反应制取茴香醛（英文）

天然产物研究与开发 ›› 2011, Vol. 23 ›› Issue (5): 815-819.

新体系下茴脑臭氧化反应制取茴香醛（英文）

于静1,2，沈敏敏1*，邓莲丽1,2，甘露1,2，哈成勇1

1中国科学院广州化学研究所纤维素化学重点实验室，广州 510650；2中国科学院研究生院，北京 100039

收稿日期:2011-03-03 出版日期:2011-10-25 发布日期:2011-09-26

Preparation of Anisaldehyde from Ozonolysis of Anethole in Water and Ethyl Acetate

YU Jing1,2, SHEN Min-min1*, DENG Lian-li1,2, GAN Lu1,2, HA Cheng-yong1

1Laboratory of Cellulose and Lignocellulosics Chemistry, Guangzhou Institute of Chemistry, Chinese Academy of Sciences, Guangzhou 510650, China; 2Graduate School of the Chinese Academy of Sciences, Beijing 100039, China

Received:2011-03-03 Online:2011-10-25 Published:2011-09-26
Supported by:
Supported by the National Key Technology R&D Program of China (No. 2007BAD82B02) and Natural Science Foundation of Guangdong province of China. (No. E06200692)

摘要/Abstract

摘要： At room temperature, anisaldehyde (4-methoxybenzaldehyde) was synthesized by the ozonolysis of anethole (1-methoxy-4-(1-propenyl)-benzene) in a solvent system composed of water and ethyl acetate. The yield of anisaldehyde from this solvent system was compared with those from the traditional solvent systems. Meanwhile, the solvent quantity, O3/O2 flow rate, water content in the mixture solvent and the reaction time which could effect on the reaction were investigated. By FTIR and UV spectrum, the reaction mechanism was investigated. In the presence of water, anethole was ozonolysed to anisaldehyde at room temperature in 100 min with a yield of 81.7%. The pure product was obtained without further isolation.

关键词: 茴脑, 茴香醛, 臭氧, 臭氧化物, 臭氧化分解

Abstract: At room temperature, anisaldehyde (4-methoxybenzaldehyde) was synthesized by the ozonolysis of anethole (1-methoxy-4-(1-propenyl)-benzene) in a solvent system composed of water and ethyl acetate. The yield of anisaldehyde from this solvent system was compared with those from the traditional solvent systems. Meanwhile, the solvent quantity, O3/O2 flow rate, water content in the mixture solvent and the reaction time which could effect on the reaction were investigated. By FTIR and UV spectrum, the reaction mechanism was investigated. In the presence of water, anethole was ozonolysed to anisaldehyde at room temperature in 100 min with a yield of 81.7%. The pure product was obtained without further isolation.

Key words: anethole, anisaldehyde, ozone, ozonide, ozonolysis

中图分类号:

TQ655

于静，沈敏敏，邓莲丽，甘露，哈成勇. 新体系下茴脑臭氧化反应制取茴香醛（英文）[J]. 天然产物研究与开发, 2011, 23(5): 815-819.

YU Jing, SHEN Min-min, DENG Lian-li, GAN Lu, HA Cheng-yong. Preparation of Anisaldehyde from Ozonolysis of Anethole in Water and Ethyl Acetate[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2011, 23(5): 815-819.