天然产物研究与开发 ›› 2014, Vol. 26 ›› Issue (5): 800-805.

• 综述 • 上一篇    

具有5α-还原酶抑制作用的天然植物的研究进展

姚新成1,顾承志2,王新兵1,秦冬梅1,唐 辉1,陈 文1*   

  1. 1 石河子大学药学院,石河子市 832000;2 石河子大学化学化工学院,石河子市 832002
  • 出版日期:2014-05-31 发布日期:2014-11-17

Review on Natural Plants with 5α-Reductase Inhibitory Effect

YAO Xin-cheng1, GU Cheng-zhi2, WANG Xin-bing1, QIN Dong-mei1, TANG Hui1, CHEN Wen1*   

  1. 1 College of Pharmacy,Shihezi University,Xinjiang Shihezi 832000,China;2 School of Chemistry and Chemical Engineering,Shihezi University,Xinjiang Shihezi 832002,China
  • Online:2014-05-31 Published:2014-11-17

摘要: 本文通过查阅国内外对5α-还原酶具有抑制作用的天然植物的研究文献,选取作用机制比较明确、临床治疗效果显著、具有大量数据验证的锯叶棕(Saw palmetto)、非洲臀果木(Pygeum africanum)、大荨麻(Urtica dioica)、苦参(Sophora flavescens)和植物花粉等天然植物进行综述。

关键词: 5&alpha, -还原酶, 酶抑制作用, 天然植物, 化学成分

Abstract: In this paper,five natural plants with 5α-reductase inhibitory effect were reviewed according to the domestic and foreign literature.The plants,namely Saw palmetto, Pygeum africanum, Urtica dioica, Sophora flavescens as well as pollen were selected based on their clear action mechanism,remarkable clinical effect and a large number of validation data on biological activity.

Key words: 5&alpha, -reductase, enzyme inhibitory effect, natural plants, chemical constituents

中图分类号: 

R914.4