关键词: 甜茶, 分离, 鉴定, 绣球酚, 降血糖活性

Abstract: To investigate the constituents of Rubus suavissimus S.Lee ,chromatographic techniques including open column,HPLCand recrystallization were employed in the isolation and purification.As a result,four constituents were obtained,and their structures were elucidated as hydrangenol(I),(E) 2(4hydroxy styrene) phenol(II),Protocatechuic acid (III)and Shikimic acid(IV) by spectral analysis and physical and chemical properties.Three compounds were obtained from Rubus suavissimus S.Lee for the first time except protocatechuic acid.And then to observe the effect of hydrangenol on blood glucose in mice.It has been found that hydrangenol has a significant hypoglycemic effect at 1w and 2w after the administration (P<0.05).

Key words: Sweet tea, isolation, identification, hydrangenol, hypoglycemic activity