天然产物研究与开发 ›› 2018, Vol. 30 ›› Issue (5): 888-899.doi: 10.16333/j.1001-6880.2018.5.025

• 综述 • 上一篇    下一篇

山竹果皮的化学成分及其药理活性研究进展

席天伦1,李晓秀1,2,刘波1*   

  1. 1沈阳医学院基础医学院;2辽宁省行为与认知神经科学重点实验室,沈阳 110034
  • 出版日期:2018-06-04 发布日期:2018-06-04
  • 基金资助:

    辽宁省自然科学基金指导计划(20170520428);辽宁省大学生创新创业训练计划(201610164001);沈阳医学院科技基金(20165054);沈阳医学院大学生科研立项(20160820;20179013);沈阳市科技计划项目(18-013-0-49)

Review on Phytochemicals and Pharmacological Activities of the Pericarp of Garcinia mangostana

XI Tian-lun1, LI Xiao-xiu1,2, LIU Bo1*   

  1. 1School of Basic Medicine,Shenyang Medical College; 2Liaoning Key Laboratory of Behavior and Cognitive Neuroscience,Shenyang 110034,China
  • Online:2018-06-04 Published:2018-06-04

摘要: 山竹不仅是一种享有“果中皇后”美誉的热带水果,同时也是一种非常具有药用价值的植物。在东南亚,山竹常被用于治疗腹痛、腹泻、发炎、皮肤感染和创伤等。现代研究表明,山竹果皮中含有丰富的氧杂蒽酮类成分,该成分具有抗肿瘤、抗氧化、酶抑制、抗原虫和微生物等药理活性。本文对近几年所报道的山竹果皮中化学成分及其药理活性研究进行综述,以期为山竹果皮的药用开发前景提供思路。

关键词: 山竹果皮, 化学成分, 药理活性, 综述

Abstract: Garcinia mangostanaL.(Clusiaceae) is a kind of tropical fruit.It has been used as traditional medicine for the treatment of diarrhoea,inflammation,skin infections and wounds in Southeast Asia.Previous studies showed that it contains high amounts of xanthenones,and these compounds exhibited a variety of pharmacological activities including anti-tumor,anti-oxidation,enzyme inhibition,antimicrobial and antiprotozoal activities.In this paper,we summarize the chemical constituents from the pericarp of Garcinia mangostana and their pharmacological activities in recent years in order to provide ideas for the development and utilization of the pericarp of G.mangostana.

Key words: pericarp of Garcinia mangostana, chemical constituents, pharmacological activities, review

中图分类号: 

R282.71 O629 Q946