Quercetin is a flavonoid compound widely present in plants and has attracted extensive attention in the scientific research community due to its potential anti-aging effect.Aging is a complex biological process involving various physiological and pathological changes,and its impact on human health is receiving increasing attention.Recent studies have shown that quercetin exerts its anti-aging effects through multiple mechanisms,including antioxidation,anti-inflammation,regulation of apoptosis and promotion of autophagy,etc.These mechanisms work together to help to slow down the aging process and may improve the occurrence and development of related diseases.In addition,quercetin exerts an anti-aging effect by interacting with the gut microbiome and improving the gastrointestinal environment to maintain the health of the body.This article reviews the potential mechanisms of quercetin in delaying aging and its medication in different populations (such as the elderly and patients with chronic diseases),aiming to summarize the current research progress,explore its application prospects,and provide references for related studies.