天然产物研究与开发 ›› 2025, Vol. 37 ›› Issue (1): 182-193.doi: 10.16333/j.1001-6880.2025.1.019 cstr: 32307.14.1001-6880.2025.1.019

• 综述 • 上一篇    

药食同源植物有效化学成分合成途径基因的组学研究进展

蔡允璋,贾巧君*   

  1. 浙江理工大学生命科学与医药学院,杭州 310018
  • 出版日期:2025-01-22 发布日期:2025-01-22
  • 基金资助:
    浙江省重点研发计划(2020C02039)

Multi-omics research progress on the synthesis pathway gene of effective chemical components in medicinal and edible homologous plants

CAI Yun-zhang,JIA Qiao-jun*   

  1. College of Life Sciences and Medicine,Zhejiang Sci-Tech University,Hangzhou 310018,China
  • Online:2025-01-22 Published:2025-01-22

摘要: 药食同源植物包含多糖、酚类、萜类等数种有效化学成分,因其保健、医疗等价值而备受关注。本文整理了已公布的药食同源植物基因组的相关研究,从转录组学、蛋白组学、代谢组学及联合分析等不同方面综述了药食同源植物中酚类、萜类、多糖、生物碱、脂质等有效化学成分的合成调控途径,总结了其细胞器基因组学的研究进展,并发现在药食同源植物中,有效化学成分合成途径的候选基因可通过模式植物转化体系进行功能验证;基因组学整合功能组学将有助于解析有效成分合成途径及其调控网络。文章旨在推动药食同源植物有效化学成分合成途径基因的组学研究进展,并为挖掘药食同源植物的药用价值提供借鉴。

关键词: 药食同源植物, 有效化学成分, 基因组学, 转录组学, 蛋白组学

Abstract:

Medicinal and edible homologous plants contain several effective chemical components,such as polysaccharides,phenols, terpenoids,etc.,and are attracted much attention for their health and medical values.This paper summarizes the published studies on the genomes of medicinal and edible homologous plants,and reviews the synthesis and regulation pathways of phenols,terpenoids,polysaccharides,alkaloids,lipids and other effective chemical component through transcriptomics,proteomics,metabolomics,and conjoint analyses.In addition,the research progress in organelle genomics is also summarized.Candidate genes for the synthesis pathway of effective components in such plants could be functionally validated through model plant transformation systems.The integration of genomics and functional genomics will help to elucidate the synthesis pathway of effective components and their regulatory networks.The article aims to promote the multi-omics research progress of effective chemical components synthesis pathways and to provide a reference for the exploitation of the medicinal value in medicinal and edible homologous plants.

Key words: medicinal and edible homologous plants, effective chemical components, genomics, transcriptomics, proteomics

中图分类号:  Q946