天然产物研究与开发 ›› 2012, Vol. 23 ›› Issue (6): 777-.doi: A

• 研究简报 • 上一篇    下一篇

茎花葱臭木化学成分的研究

唐 霆1,2,纳 智1,许又凯1,3*   

  1. 1中国科学院西双版纳热带植物园热带森林生态学重点实验室,勐腊 666303;2中国科学院研究生院,北京 100049;3中国科学院西双版纳热带植物园热带植物资源开放实验室,勐腊 666303
  • 收稿日期:2010-12-15 出版日期:2012-07-04 发布日期:2012-07-06

Chemical Constituents from Dysoxylum cauliflorum (Meliaceae)

TANG Ting1,2, NA Zhi1, XU You-kai1,3*   

  1. 1Key Laboratory of Tropical Forest Ecology, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Mengla 666303, China; 2 Graduate University of the Chinese Academy of Sciences, Beijing 100049, China; 3 Laboratory of Tropical Plant Resource Science, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Mengla 666303, China
  • Received:2010-12-15 Online:2012-07-04 Published:2012-07-06
  • Supported by:

    This study was supported by the Knowledge Innovation Project of Chinese Academy of Sciences (KSCX2-YW-R-172).

摘要: 从茎花葱臭木种子中分离得到5个化合物,经理化与波谱分析鉴定为β-谷甾醇(1)、没食子酸乙酯(2)、胡萝卜苷(3)、1-O-β-D-吡喃葡萄糖基-(2S,3S,4R,8Z)-2-N-(2′-羟基二十四烷酰氨基)十八二氢鞘氨-8-烯(4)和2,3,2″,3″-四氢穗花杉双黄酮(5)。这5个化合物均首次从该植物中分离得到。其中化合物5进行细胞毒活性测试,没有显示抑制活性。

关键词: 茎花葱臭木;楝科;2,3,2&Prime, ,3&Prime, -四氢穗花杉双黄酮;细胞毒活性

Abstract: Five compounds were isolated from the seeds of Dysoxylum cauliflorum and their structures were elucidated as β-sitosterol (1), ethyl gallate (2), daucosterol (3), 1-O-β-D-glucopyranosyl-(2S,3S,4R,8Z)-2-N-(2′-hydroxytetracosanoyl) octadecasphinga-8-ene (4), and 2,3,2″,3″-tetrahydroamentoflavone (5). All of these compounds were isolated from this plant for the first time. Compound 5 was evaluated for cytotoxicity against five human cancer cell lines but showed no inhibitory activities.

Key words: Dysoxylum cauliflorum, Meliaceae, 2,3,2″,3″-tetrahydroamentoflavone, cytotoxicity

中图分类号: 

Q946.91 R284.1 R284.2