大管的化学成分研究

doi:A

摘要/Abstract

摘要： 从小芸木属植物大管茎皮部位共分离得到12个化合物，运用MS、1H-NMR和13C-NMR等波谱方法并结合文献对照分别鉴定为5-formyl-6,7-dimethoxycoumarin（1），isoscoploletin-β-D-glucoside（2），6-(trans-1-buten-3-only)-7-methoxycoumarin（3），6-羟基-7-甲氧基香豆素（4），microfalcatin isovalerate（5），小芸木宁（6），丁香苷（7），coniferin（8），methyl 2-O-β-D-glucopyranosylbenzoate（9），2-hydroxy-5-methoxy-trans-cinnamic acid（10），3,5-二甲氧基-4-羟基苯甲醛（11）和邻仲丁基苯酚（12）。其中化合物1为新的天然产物；除5和6外，其余化合物均首次从该植物中分离得到。

关键词: 大管, 香豆素, 芳香类化合物

Abstract: Twelve compounds were isolated from Micromelum falcatum and purified by repeated column chromatography on silica, Sephadex LH-20 gel, and HPLC and structurally identified by spectral analysis. The compounds were identified as 5-formyl-6,7-dimethoxycoumarin (1), isoscoploletin-β-D-glucoside (2), 6-(trans-1-buten-3-only)-7-methoxycoumarin (3), isoscopoletin-(6-hydroxyl-7-methoxyl coumarin, isoscopoletin) (4), microfalcatin isovalerate (5)，micromelin(6), syringin (7), coniferin (8), Methyl 2-O-β-D-glucopyranosylbenzoate (9), 2-hydroxy-5-methoxy-trans-cinnamic acid (10), 3,5-dimethoxyl-4-hydroxyl benzaldehyde (11) and o-sec-butyl phenol (12). Compound 1 previously synthesized but first isolated as natural product, and the other compounds were isolated from this plant for the first time except 5 and 6.

Key words: Micromelum falcatum, coumarins, aromatic compounds

中图分类号:

R284.2

黄永中，张偲，黄升，罗雄明，王建华. 大管的化学成分研究[J]. 天然产物研究与开发, 2012, 23(09): 1161-.

HUANG Yong-zhong, ZHANG Si, HUANG Sheng, LUO Xiong-ming, WANG Jian-hua. Chemical Constituents of the Plant Micromelum falcatum (Lour.) Tan.[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2012, 23(09): 1161-.

参考文献

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