珍稀药用植物明党参呋喃香豆素成分累积分布研究

doi:A

天然产物研究与开发 ›› 2012, Vol. 23 ›› Issue (4): 510-513.doi: A

珍稀药用植物明党参呋喃香豆素成分累积分布研究

张莹¹，陈建伟^1,2*，李　祥^1,3，顾源远¹

¹南京中医药大学药学院，南京 210046；²江苏省方剂研究重点实验室，南京 210046；³江苏省中药炮制重点实验室，南京 210029

收稿日期:2011-01-26 出版日期:2012-04-26 发布日期:2012-05-16
基金资助:
教育部高等学校博士学科点专项科研基金资助课题（200803150009），江苏高校优势学科建设工程资助项目，江苏省自然科学基金（BK2003107），国家药典研究项目（YZ-124）

Accumulation and Distribution of Furanocoumarins in Rare Medicinal Plants Changium smyrnioides Wolff

ZHANG Ying¹, CHEN Jian-wei^1,2*, LI Xiang^1,3, GU Yuan-yuan¹

¹Pharmacology College of Nanjing University of Chinese Medicine, Nanjing 210046, China; ²Jiangsu Key Laboratory for TCM Formulae Research, Nanjing 210046, China;³Jiangsu Key Laboratory for Chinese Material Medical Processing, Nanjing 210029, China

Received:2011-01-26 Online:2012-04-26 Published:2012-05-16

摘要/Abstract

摘要： 采用HPLC法测定明党参不同器官、不同生长期中珊瑚菜内酯、5-羟基-8-甲氧基补骨脂素的含量。结果表明，明党参根、茎叶、花葶及果实均含有2种呋喃香豆素，2种呋喃香豆素总量，根中以6月为最高，为163.8467 ?g/g；茎叶以1月为最高，为606.1023 ?g/g；花葶以6月上旬（生长发育接近成熟时）为最高，为117.1185 ?g/g；果实以成熟期为最高，达1070.6326 ?g/g。提示明党参药用器官（根）和非药用器官（茎叶、花葶、果实）为天然呋喃香豆素优质药用植物资源，具有广泛开发利用的前景。

关键词: 明党参, 呋喃香豆素, 珊瑚菜内酯, 5-羟基-8-甲氧基补骨脂素, 累积分布

Abstract: HPLC method was used to determine the contents of phellopterin and 5-hydroxyl-8- methoxy-psoralen in Changium smyrnioides Wolff collected from different organs and different periods of growth. The results showed that roots, stems, leaves, scapes and fruits of C. smyrnioides contain two furanocoumarins. In the roots, the total contents of two furanocoumarins were highest in June reaching 163.8467 ?g/g. In the stems and leaves, the contents were highest in January reaching 606.1023 ?g/g. In the scapes, the contents were highest in early June when the scapes were grown close to maturity reaching 117.1185 ?g/g. Furanocoumarins in fruit of C. smyrnioides (to maturity) was the highest, and reached 1070.6326 ?g/g. C. smyrnioides is a high quality medicinal plant resource for natural furanocoumarins, including the medicinal and the non-medicinal parts of the plant. It has great potential that is worthy for further exploration.

Key words: Changium smyrnioides Wolff, furanocoumarins, phellopterin, 5-hydroxyl-8-methoxy psoralen, cumulative distribution

中图分类号:

R282.7

张莹，陈建伟，李　祥，顾源远. 珍稀药用植物明党参呋喃香豆素成分累积分布研究[J]. 天然产物研究与开发, 2012, 23(4): 510-513.

ZHANG Ying, CHEN Jian-wei, LI Xiang, GU Yuan-yuan. Accumulation and Distribution of Furanocoumarins in Rare Medicinal Plants Changium smyrnioides Wolff[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2012, 23(4): 510-513.

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珍稀药用植物明党参呋喃香豆素成分累积分布研究

Accumulation and Distribution of Furanocoumarins in Rare Medicinal Plants Changium smyrnioides Wolff

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