α-Glucosidase Inhibitory and Antioxidant Activity of Magnolia Officinalis

doi:A

Abstract

Abstract: The α-glucosidase inhibitory activities of Magnolia officinalis from Guizhou and Henan province was assayed by the method of 96-microplates for the first time, and its antioxidant activity was determined by the method of DPPH, ABTS and FRAP. Ethyl acetate (IC50 = 7.22 μg/mL) and methanolic extracts (IC50 =36.59 μg/mL) of M. officinalis from Guizhou, and the petroleum ether (IC50 = 107.04 μg/mL) and ethyl acetate extracts (IC50 =17.17 μg/mL) of M. officinalis from Henan were higher than that of Acarbose (IC50=1081.27 μg/mL) as positive control. Ethyl acetate extracts of M. officinalis from Guizhou had the highest ABTS free radical scavenging activity (IC50 = 8.81 μg/mL), which was higher than that of BHT（IC50 = 11.94 μg/mL）as positive control, and followed by ethyl acetate extracts of Magnolia officinalis from Henan (IC50 =12.73 μg/mL).The results indicated that ethyl acetate extracts of M. officinalis from Guizhou showed the strongest activity of α-glucosidase inhibitory activity and antioxidant activity.

Key words: Magnolia officinalis, α-glucosidase inhibitory activity, antioxidant activity

CLC Number:

Q946.81

CAO Nai-feng , KANG Wen-yi. α-Glucosidase Inhibitory and Antioxidant Activity of Magnolia Officinalis[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2012, 23(8): 1118-.

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