Abstract: The resveratrolchitosan microcapsule was prepared using spray drying method.The loading capacity and entrapment efficiency and product yield were used to evaluate the influences of different formulations and preparation factors.The optimal formulation and preparation conditions were determined as follows:1:4 as ratio of resveratro1 to chitosan,0.5% as chitosan concentration,9 mL/min as sampling speed,165 ^oC as inlet temperature.Under the optimized conditions,the loading capacity of microcapsule was 16.87%.The entrapment efficiency was 63.05%.The product yield was 43.68%.The preparation method developed in this study was simple,and the process was stable.It will provide the basis for realizing the industrialization in Chinese materia medica microcapsule.

Key words: resveratrol, chitosan, technology, microcapsule, spray drying