Eleven terpenoids were isolated and purified from the ethanol extract of Callicarpa kwangtungensis of Lingnan Herbs.Based on spectral analysis and the comparition of literatures,these compounds were identified as sambucunlin A(1),2α-hydroxy-lupeol(2),swinhoeic acid(3),3β-hydroxy-urs-11-en-13β,28-olide(4),euscaphic acid(5),2α,3β,6β,18β,23-pentahydroxy-olean-12-en-28-oic acid(6),rel-5-(3S,8S-dihydroxy-1R,5S-dimethyl-7-oxa-6-oxobicyclo-oct-8-yl)-3-methyl-2Z,4E-pentadienoic acid(7)and salvionoside B(8),oleanolic acid(9),betulinic acid(10),α-amyrin(11),respectively.Compounds 1-4,6-8 was firstly isolated from the genus of Callicarpa.Further the lipopolysaccharide (LPS)-induced RAW 264.7 mouse macrophages was explored as inflammatory model to measure the anti-inflammatory activity of the terpenoids.The experimental results revealed that compounds 3 and 9 had obvious anti-inflammatory activity.It was found that the anti-inflammatory activity of triterpenoids (3-6,9 and 11)was better than that of sesquiterpenoids (7 and 8).This study provided the experimental basis for the clinical application of C. kwangtungensis in anti-inflammatory fields．