The metabolites of an endophytic Aspergillus sp. from the intestine of Aspongopus chinensis were studied in tihis paper.Six compounds were isolated from rice solid fermentation extract by silica gel column chromatography,MCI column chromatography,gel column chromatography and semi preparative liquid method.The structures of the six compounds were analyzed by NMR and mass spectrometry,including a new compound flavion (1) and five known compounds citreovirenone (2),kojic acid (3),methyl chloroacetate (4),aspulvinone P (5) and aspulvinone Q (6).Compounds 1 and 2 were isolated from Aspergillus for the first time.Compounds 3 and 4 exhibited weak antimicrobial effects with MIC values ranging from 35.5 to 67.5 μg/mL.