Isolation and Identification of Secondary Metabolites from Xenorhabdus budapestensis SN19

Abstract

Abstract: Two depsipeptides were isolated and purified from secondary metabolites of Xenorhabdus budapestensis SN19 by silica gel column chromatography,Sephadex LH-20 chromatography and semi-preparative high-performance liquid chromatography.Their structures were identified as xenematides C (1) and xenematides E (2) using nuclear magnetic resonance (NMR) and mass spectroscopy (MS).Xenematides E (2) was a new compound.Xenematides C (1) showed a strong inhibition activity against Botrytis cinerea (EC₅₀=22.71 μg/mL).

Key words: nematode symbiotic bacteria, secondary metabolites, depsipeptide, antifungal

CLC Number:

S482.7

LU Xing-zhong, SHI Dan-shu, GAO Chun-zhi, TIAN Xiao-mei, BI Yu-hui, YU Zhi-guo , . Isolation and Identification of Secondary Metabolites from Xenorhabdus budapestensis SN19[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2016, 28(6): 829-832.

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Isolation and Identification of Secondary Metabolites from Xenorhabdus budapestensis SN19

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