Effect of Lepidium meyenii (Maca) Ethanol Extract on Endocrine Hormone Levels in Climacteric Rats

doi:10.16333/j.1001-6880.2016.8.006

Abstract

Abstract: In order to study the effect of Lepidium meyenii (Maca) ethanol extract on endocrine hormone levels in blood serum of climacteric body,the naturally aged female rats were used as a model and randomly divided into low,medium and high dosage groups,positive and negative control groups.Maca ethanol extract were given to rats continuously by oral gavage for 90 days.The variations of body weight,organ index and endocrine hormone levels ［serum estradiol (E2),luteinizing hormone (LH),follicle stimulation hormone (FSH),testosterone (T),progesterone (P) and pituitary prolactin (PRL)］ in blood serum were then analyzed.As a result,the body weight was decreased by feeding with different dosages of Maca extract and the organ index of liver,spleen and kidney were higher than those of control group.The levels of T,LH and P in serum were significantly changed (P<0.05).The symptoms of menopause maybe alleviated by Maca ethanol extract through regulating the secretion and metabolism.

Key words: Maca, rat, climacteric syndrome, endocrine hormone

CLC Number:

R151.3

HAN Bei1,FU Gui-ming2,3,CAI Kun4,ZHANG Bao-xiang4,ZHANG Rui-juan1*. Effect of Lepidium meyenii (Maca) Ethanol Extract on Endocrine Hormone Levels in Climacteric Rats[J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2016, 28(8): 1207-1211.

Add to citation manager EndNote|Ris|BibTeX

URL: http://www.trcw.ac.cn/EN/10.16333/j.1001-6880.2016.8.006

http://www.trcw.ac.cn/EN/Y2016/V28/I8/1207

[1]	JIANG Wen, LIU Xian-jun, ZHENG Yu-feng, LIU Yue, MENG Xiang-long, LI Zhan-dong, LI Hao, YIN Yu-he. Improvement effect and mechanism of gastrodigenin on dextran sulfate sodium-induced ulcerative colitis in mice [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(5): 919-928.
[2]	HUANG An-li, MA Ke-yu, LI Bo-rui, HOU Bao-long, LIANG Yan-ni, WANG Zheng. Mechanism of Xianglian Pill in improving ulcerative colitis based on metabolomics [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(5): 929-941.
[3]	FAN Hao, WANG Xin, WU Yi-xuan, ZHANG Dong-dong, WANG Wei, SONG Xiao-mei, LI Yu-ze, DENG Chong. Secondary metabolites from endophytic fungus Aspergillus sp.FH-2 in Valeriana officinalis L. based on the OSMAC strategy [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(5): 989-995.
[4]	DONG Xiao-li, XIE Xing-wen, LI Rui-ting, ZHANG Jia-xu, MA Qu-huan, SHI Xiao-feng. Purification process of total flavonoids from Eucommia ulmoides leaves based on Box-Behnken response surface method [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(5): 1007-1016.
[5]	CHEN Ming-ju, LI Chang-ke, HUANG Sheng, YOU Shuang-si, LI Ling-qian, ZHANG Ting-ting, CHEN Xing-fu. Effects of formulated fertilization on the yield and main active components of Angelica dahurica var. formosana [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(5): 1017-1028.
[6]	SHAO Bing-mei, CUI Jun-li, TIAN Jing-zhen, HOU Lin. Anti-respiratory syncytial virus mechanism of Callicarpae Nudiflorae Folium based on the p38 MAPK/NF-κB signaling pathway [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(5): 1058-1065.
[7]	ZHANG Zi-an, CHEN Fan, ZHANG Liang-qi, CHEN Wang, LIU Sai-hu, HE Fu-yuan, XIAO Mei-feng. "Imprinting templates" differences and spectral-quantitative study of Lonicerae Japonicae Flos and Lonicerae Flos [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(4): 815-826.
[8]	FU Ke, ZHANG Ya-fang, ZENG Li, PU Shi-yun. Research progress on the biological activities,extraction and separation of eleutheroside B [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(4): 897-909.
[9]	CAI Jia-qi, ZHANG Xue-ping, YUN Liang, CHEN Yi-chun, WANG Xu, ZHU Kai, YANG Jing, ZHANG Kui. A dataset of the process and composition of tobacco flavor prepared from tobacco stems [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(4): 914-917.
[10]	TAI Lun-wei, SONG Sheng-you, MENG Ning-ning, JIANG Jun-ling, SHANG Guan-wei, WU Jing-qiang, ZHAO Jun-feng. Study on the regulation of biological behaviors in renal carcinoma Renca cells by lathyrol via hnRNP K modulation [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(3): 573-580.
[11]	WU Yi, HUANG Zi-luo, LI Xue-shan, SHI Hui-ying, CHEN Guan-rong, FENG Jie, ZHONG Xiao-bin. Therapeutic effects and mechanisms of cambogin in the treatment of ulcerative colitis based on network pharmacology and in vitro experimental validation [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(3): 627-636.
[12]	JIN Feng, TANG Zhi-shu, SONG Zhong-xing, JIAO Hong-hong. Research progress on alkaloid chemical constituents of Corydalis yanhusuo and their extraction and separation,analysis and detection,and pharmacological activities [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(3): 648-661.
[13]	JIANG Bo-ling, FENG Chun, ZHENG Rong. Effects of salidroside on chemotherapy resistance in ovarian cancer cells by regulating FOXO3-FOXM1 signaling axis [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(2): 262-272.
[14]	LUAN Fei, WANGN He, LEI Zi-wen, WANG Wei-xiang, WANG Zhi-chao, ZHANG Xiao-fei, ZOU Jun-bo, SHI Ya-jun. Comparison of the changes in chemical components before and after the combination of Cinnamomi Ramulus and Glycyrrhizae Radix et Rhizoma Praeparata cum Melle by UPLC-Q-TOF-MS/MS [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(2): 283-293.
[15]	XU Jia-hui, LI Xin, HUO Jing-chen, CUI Chun-li, ZHANG Ying, MA Yu-lin, ZHANG Juan. Pharmacodynamics and preparation of aloperine thermosensitive gel for vaginal use [J]. NATURAL PRODUCT RESEARCH AND DEVELOPMENT, 2026, 38(1): 94-106.

Effect of Lepidium meyenii (Maca) Ethanol Extract on Endocrine Hormone Levels in Climacteric Rats

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments