Abstract: Gut microbiota,tea and tea polyphenols are closely related to obesity and comorbidity,and the interaction between them is a hotspot in the field of food,medicine and biology.On one hand,the bioconversion of tea polyphenols and other ingredients by gut microbiota improves the bioavailability of tea and tea polyphenols,which is more conducive to the regulation of obesity and comorbidity.On the other hand,tea and tea polyphenols can affect the composition and function of gut microbiota and thus affect the development of obesity and comorbidity.This paper reviews the regulation effect of gut microbiota,tea and tea polyphenols and their interaction on obesity and comorbidity.Besides,the mechanism of tea and tea polyphenols for regulating obesity and comorbidity through gut microbiota is summarized,aiming to provide valuable references for study on active ingredients of tea and its product development.

Key words: gut microbiota, obesity, tea, tea polyphenols, interaction, regulatory mechanism