NATURAL PRODUCT RESEARCH AND DEVELOPMENT ›› 2014, Vol. 26 ›› Issue (9): 1402-1406.

• Article • Previous Articles     Next Articles

Structure and Biological Activity of the La(Ⅲ) Complex with Apigenin

YANG Yun-shang1*, TAO Lian-chun1, ZHANG Ying-peng1, SUN Shi-qi2, GUO Hui-chen2*   

  1. 1 School of Petrochemical Technology,Lanzhou University of Technology,Lanzhou 730050 ,China; 2 State Key Laboratory of Veterinary Etiological Biology, National Foot and Mouth Disease Reference Laboratory,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences, Lanzhou 730046 ,China
  • Online:2014-09-30 Published:2014-11-02

Abstract: The La(III) complex with apigenin was first synthesized through lanthanum nitrate with apigenin, the complex was characterized by elemental analysis, molar conductance, IR, 1H-NMR, TG-DSC. The scavenging effect on the superoxide radical (O2-·),hydroxyl radical (·OH)and the antitumor activity on cervical cancer cells with complex were also studied. The results showed that the molecular formula of the complex is La(C15H9O5)2NO3·1.5H2O and it has stronger antioxidant activity and antitumor activity.

Key words: apigenin, La(III) complex, antioxidative activity, antitumor activity

CLC Number: