天然产物研究与开发 ›› 2017, Vol. 29 ›› Issue (1): 52-57.doi: 10.16333/j.1001-6880.2017.1.009

• 研究简报 • 上一篇    下一篇

中国海南半红树植物海漆的化学成分研究

莫德娟,李敏一*   

  1. 暨南大学药学院海洋药物研究中心,广州 510632
  • 出版日期:2017-01-31 发布日期:2017-02-17

Chemical Constituents of Semi-Mangrove Plant Excoecaria agallocha L.

MO De-juan,LI Min-yi*   

  1. Marine Drugs Research Center,College of Pharmacy,Jinan University,Guangzhou 510632,China
  • Online:2017-01-31 Published:2017-02-17

摘要: 对生长于中国海南的半红树植物海漆(Excoecaria agallocha L.)的化学成分进行分离鉴定。用硅胶柱层析,凝胶柱层析和高效液相色谱对海漆的乙酸乙酯萃取物进行分离纯化,从中分离得到15个化合物,并运用现代波谱技术分别鉴定为:(±)-丁香脂素(1)、(+)-麦迪奥脂素(2)、(±)-buddlenol C(3)、threo-buddlenol C(4)、(±)-ficusesquilignan A(5)、(-)-(7R,7′R,7′′S,8S,8′S,8′S)-4′,4′′-dihydroxy-3,3′,3′′,5,5′,5′′-hexamethoxy-7,9′:7′,9-diepoxy-4,8′′-oxy-8,8′-sesquineolignan-7′′,9′′-diol(6)、salicifoliol(7)、臭矢菜素C(8)、curcasinlignan A(9)、东莨菪亭(10)、秦皮素(11)、异秦皮素(12)、金色酰胺醇(13)、金色酰胺醇酯(14)、丁香醛(15)。其中化合物2~15均为首次从该种植物中分离得到。

关键词: 半红树植物, 海漆, 化学成分, 木脂素

Abstract: The chemical constituents of semi-mangrove Excoecaria agallocha L. collected at Hainan island,China were isolated by silica gel column chromatography and preparative HPLC.Fifteen compounds were finally obtained from the EtOAc extract of E.agallocha L.On the basis of modern spectral data,they were identified as (±)-syringaresinol (1), (+)-medioresinol (2), (±)-buddlenol C (3), threo-buddlenol C (4),(±)-ficusesquilignan A (5),(-)-(7R,7′R,7′′S,8S,8′S,8′′S)-4′,4′′-dihydroxy-3,3′,3′′,5,5′,5′′-hexamethoxy-7,9′:7′,9-diepoxy-4,8′′-oxy-8,8′- sesquineolignan-7′′,9′′-diol(6),salicifoliol (7),cleomiscosin C (8),curcasinlignan A (9),scopoletin (10),fraxidin (11),iso-fraxidin (12),aurantiamide (13),aurantiamide acetate (14),syringaldehyde (15).Compounds 2-15 were isolated from this plant for the first time.

Key words: semi-mangroves, Excoecaria agallocha L., chemical constituent, lignan

中图分类号: 

R93