天然产物研究与开发 ›› 2017, Vol. 29 ›› Issue (10): 1642-1647.doi: 10.16333/j.1001-6880.2017.10.002

• 研究论文 • 上一篇    下一篇

潞党参化学成分研究

郑涛1,2,晏永明3,徐福荣2,程永现1,2,3*   

  1. 1中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,昆明 650201;2云南中医学院,昆明 650500;3深圳大学医学部药学院,深圳 518060
  • 出版日期:2017-10-27 发布日期:2017-10-27
  • 基金资助:

    云南省生物科技重大项目(2014FC002)

Compounds from Codonopsis pliosula

ZHENG Tao1,2, YAN Yong-ming3, XU Fu-rong2, CHENG Yong-xian1,2,3*   

  1. 1State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany, Chinese Academy of Sciences,Kunming 650201,China; 2Yunnan University of Traditional Chinese Medicine,Kunming  650500,China; 3School of Pharmaceutical Sciences,Shenzhen University Health Science Center,Shenzhen 518060,China
  • Online:2017-10-27 Published:2017-10-27

摘要: 采用色谱法从潞党参中分离得到22个化合物,利用波谱学方法鉴定了它们的结构,分别命名为7-ethyoxy tangshenoside Ⅱ(1)、tangshenoside Ⅱ(2)、4-hydroxycinnamyl-O-β-D-glucopyranoside(3)、juniperoside(4)、2-phenylethyl-β-D-glucopyranoside(5)、syringoside(6)、ethylsyringin(7)、(+)-isolariciresinol(8)、lariciresinol(9)、7R,8S-dihydrodehydrodiconiferyl alcohol(10)、vitrifol A(11)、sesquimarocanol B(12)、4-hydroxycinnamate(13)、protocatechuic acid methyl ester(14)、trans-ferulic acid(15)、para-hydroxy benzoic acid(16)、cis-ferulic acid(17)、胸腺嘧啶(18)、尿嘧啶核苷(19)、尿嘧啶(20)、4-methoxybenzene-1,2-diol(21)和5-hydroxymethyl-5H-furan-2-one(22)。其中化合物1为新化合物,化合物2~5、8~12以及化合物18、19均为首次从潞党参中被分离得到。

关键词: 潞党参, 桔梗科, 化学成分, 苯丙素苷, 木脂素

Abstract: One new compound,7-ethyoxy tangshenoside Ⅱ (1),along with 21 known compounds were isolated from Codonopsis pilosula.The known compounds were identified as tangshenoside Ⅱ (2),4-hydroxycinnamyl-O-β-D-glucopyranoside (3),juniperoside (4),2-phenylethyl-β-D-glucopyranoside (5),syringoside (6),ethylsyringin (7),(+)-isolariciresinol (8),lariciresinol (9),7R,8S-dihydrodehydrodiconiferyl alcohol (10),vitrifol A (11),sesquimarocanol B (12),4-hydroxycinnamate (13),protocatechuic acid methyl ester (14),trans-ferulic acid (15),para-hydroxy benzaldehyde (16),cis-ferulic acid (17),thymine (18),1-beta-L-xylofuranosylpyrimidine-2,4 (1H,3H)-dione (19),2,4-(1H,3H-Pyrimidinedione) (20),4-methoxybenzene-1,2-diol (21),and 5-hydroxymethyl-5H-furan-2-one (22),respectively,by spectroscopic methods.With exception of new substance (1),compounds 2-5,8-12,18 and 19 were isolated from this species for the first time.

Key words: Codonopsis pliosula, Campanulaceae, chemical constituents, phenylpropanoid glycoside, lignans

中图分类号: 

Q93