天然产物研究与开发 ›› 2018, Vol. 30 ›› Issue (12): 2056-2062.doi: 10.16333/j.1001-6880.2018.12.004

• 研究论文 • 上一篇    下一篇

红豆树茎枝中黄酮类成分及其抑菌活性研究

邱亚铁1,石妍1,徐会有1,倪林1,3*,陈启建1,何碧珠3,卢海啸2*   

  1. 1福建农林大学植物保护学院,福州 350002;2玉林师范学院 广西农产资源化学与生物技术重点实验室,玉林 537000;3福建农林大学 自然生物资源保育利用福建省高校工程研究中心,福州 350002
  • 出版日期:2019-01-02 发布日期:2019-01-02
  • 基金资助:

    国家自然科学基金(31700292);广西农产资源化学与生物技术重点实验室开放基金

Flavonoids from the Twigs of Ormosia hosiei and Their Anti-fungal Activities

QIU Ya-tie1,SHI Yan1,XU Hui-you1,NI Lin1,3*,CHEN Qi-jian1,HE Bi-zhu3,LU Hai-xiao2*   

  1. 1College of Plant Protection,Fujian Agriculture and Forestry University,Fuzhou  350002,China; 2Yulin Normal University,Guangxi Key Laboratory of Agricultural Resources Chemistry and Biotechnology,YuLin 537000,China; 3Fujian Colleges and Universities Engineering Research Institute of Conservation & Utilization of Natural Bioresources,Fujian Agriculture and Forestry University,Fuzhou 350002,China
  • Online:2019-01-02 Published:2019-01-02

摘要: 为了研究红豆树茎枝抑菌活性成分,采用色谱法分离纯化得到16个黄酮类化合物,通过理化性质及波谱技术分别鉴定为圆荚草双糖苷(1)、5,7-二羟基-4′-甲氧基异黄酮-7-O-β-D-葡萄糖苷(2)、4′,8-二甲氧基-7-O-β-D-葡萄糖基异黄酮(3)、芒柄花苷(4)、异樱黄素-7-O-β-D-葡萄糖苷(5)、芦丁(6)、山奈酚-3-O-β-D-芸香糖苷(7)、4′-甲氧基异黄酮-7-O-β-D-木糖(1→6)-O-β-D-吡喃葡萄糖苷(8)、4′-甲氧基异黄酮-7-O-β-D-芹糖(1→6)-O-β-D-吡喃葡萄糖苷(9)、染料木素(10)、异樱黄素(11)、2′,4′,5,7-四羟基异黄酮(12)、大豆素(13)、柚皮素(14)、二氢染料木素(15)、去甲基化美迪紫檀素(16)。其中化合物1~16为首次从红豆树植物中分离得到;化合物1、3、4、6~9、12、15、16首次从红豆属中分离得到;化合物2,5和14对禾谷镰刀菌、西瓜尖镰孢菌、茄病镰刀菌的菌丝生长显示出了中等强度的抑制作用。

关键词: 红豆树, 红豆属, 黄酮, 异黄酮, 抑菌

Abstract: To investigate anti-fungal constituents from the twigs of Ormosia hosiei.Sixteen flavonoids were isolated and purified by column chromatography.Their structures were elucidated on the basis of physico-chemicial properties and spectral analysis as sphaerobioside (1),sissotrin (2),4′,8-dimethoxyl-7-O-β-D-glucopyranosyl isoflavone (3),ononin (4),isoprunetin-7-O-β-D-glucoside(5),rutin (6),kaempferol-3-O-β-D-rutinoside (7),kushenol O (8),7-hydroxy-4′-methoxylisoflavone-7-O-β-D-apiofuranosyl-(1→6)-O-β-D-glucopyranoside (9),genistein (10),isoprunetin (11),2′,4′,5,7-tetrahydroxyisoflavone (12),daidzein (13),naringenin (14),dihydrogenistein (15) and demethylmedicarpin (16).Compounds 1-16 are obtained from O.hosiei for the first time,and compounds 1,3,4,6-9,12,15,16 are obtained from the genus of Ormosia for the first time.Compounds 2,5,and 14 showed moderate inhibitory activities to the mycelial growth of Fusarium graminearum,Fusarium oxysporumf and Fusarium solani.

Key words: Ormosia hosiei, Ormosia, flavonoids, isoflavones, anti-fungi

中图分类号: 

R284 Q961