天然产物研究与开发 ›› 2021, Vol. 33 ›› Issue (10): 1797-1807.doi: 10.16333/j.1001-6880.2021.10.020

• 综述 • 上一篇    

中药糖蛋白的研究进展

唐雅楠,韩喜桃,刘子琴,杜红*


  

  1. 北京中医药大学中药学院,北京 102488
  • 出版日期:2021-10-28 发布日期:2021-10-28
  • 基金资助:
    国家重点研发计划“中医药现代化研究”重点专项(2018YFC1706303)

Research progress on glycoprotein of Chinese materia medica

TANG Ya-nan,HAN Xi-tao,LIU Zi-qin,DU Hong*   

  1. School of Chinese Materia Medica,Beijing University of Chinese Medicine,Beijing 102488,China
  • Online:2021-10-28 Published:2021-10-28

摘要: 糖蛋白是寡糖与多肽链共价连接的结合蛋白质,广泛存在且具有显著药用功效和保健功能,如抗氧化、抗肿瘤、免疫调节等。本文对近年来中药糖蛋白的提取、分离纯化、结构鉴定及药理作用的研究进行概述,探讨糖蛋白是否能够作为中药材发挥药效的物质基础之一,进一步开发应用。

关键词: 中药, 糖蛋白, 提取, 分离纯化, 结构鉴定, 药理作用

Abstract:

Glycoprotein is a type of binding protein formed by covalently connecting oligosaccharides and polypeptide chains,which is widely present in variety,and have significant therapeutic and health care effects,such as anti-oxidation,anti-tumor and immune regulation,etc.In this paper,the studies of extraction,isolation and purification,structure identification and pharmacological actions of glycoproteins of Chinese materia medica in recent years are summarized,to discuss whether glycoproteins can be used as one of the material bases for Chinese materia medica to exert its efficacy and be further developed and applied.

Key words: Chinese materia medica, glycoprotein, extraction, isolation and purification, structure identification, pharmacological actions

中图分类号:  R284.2