天然产物研究与开发 ›› 2025, Vol. 37 ›› Issue (10): 1974-1983.doi: 10.16333/j.1001-6880.2025.10.018 cstr: 32307.14.1001-6880.2025.10.018

• 综述 • 上一篇    

中药挥发性成分治疗肺系疾病的药理研究进展

胡宏迪1,吕  尚1,2*,闫凤秋1,饶  毅1,2*   

  1. 1江西中医药大学,南昌 330000;2中药固体制剂制造技术国家工程研究中心,南昌 330006
  • 出版日期:2025-10-31 发布日期:2025-10-30
  • 基金资助:
    中国博士后科学基金第七十三批面上资助项目(2023 M731439);江西省自然科学基金(20224BAB216099);江西省药监局科研项目(2022JS27);江西中医药大学校级科技创新团队发展计划(团队编号:CXTD22015)

Pharmacological research progress on volatile components of traditional Chinese medicine in lung diseases treatment

HU Hong-di1,LYU Shang1,2*,YAN Feng-qiu1,RAO Yi1,2*   

  1. 1Jiangxi University of Chinese Medicine,Nanchang 330000,China; 2National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine,Nanchang 330006,China
  • Online:2025-10-31 Published:2025-10-30

摘要:

肺系疾病是临床常见疾病,患者以儿童和老人居多。由于缺少系统性治疗手段,临床仍处于药物缺乏的困境。研究表明中药挥发性成分结构多为小分子萜类、倍半萜类等,是中药药效物质基础之一。针对肺系疾病病机中的外邪入侵,肃降失调,中药挥发性成分以其升阳解表,宣肺降气的作用特点,在治疗肺系疾病中展现出抗炎、抗氧化、抗菌、抗病毒、调节免疫等药理作用。本文对中药挥发性成分治疗肺系疾病的药理研究进展进行了系统性回顾,为中药挥发性成分的深入研究和开发利用提供参考。

关键词: 中药挥发性成分, 肺系疾病, 药理研究, 抗炎, 抗氧化, 抗病毒

Abstract:

Lung diseases are common clinical diseases,and most patients are children and the elderly.Due to the lack of systematic treatment methods,the clinic is still in a dilemma of drug shortage.The structures of volatile components of traditional Chinese medicine are mostly small molecule terpenes,sesquiterpenes,etc.,which are one of the pharmacological substances.In response of the pathogenesis “the invasion of exogenous evil” and “impaired depurative downbearing” in lung diseases,the volatile components of traditional Chinese medicine can raise yang and relieve exterior symptoms,promot dispersing and descending lung qi,and in modern pharmacological research,they show anti-inflammatory,antioxidant,antibacterial,antiviral,and immune regulation effects in the treatment of lung diseases.This article systematically reviews the pharmacological research progress on volatile components of traditional Chinese medicine for lung diseases treatment,in order to provide basis and ideas for further research and development and utilization of volatile components of traditional Chinese medicine.

Key words:

中图分类号:  R285.5